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| A comprehensive overview and four review articles that demystify the molecular mechanisms underlying lymphocytes' unique recombination events and specific gene expression programs. |
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| Editorial | Top |
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Focus on Chromatin Dynamics (Un-)Braiding the genome p601 doi:10.1038/ni0703-601 Full text | PDF
(49K)
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| Overview | Top |
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Focus on Chromatin Dynamics Chromatin dynamics and locus accessibility in the immune system pp603 - 606 Raul Mostoslavsky, Frederick W Alt
& Craig H Bassing doi:10.1038/ni0703-603 Abstract | Full text | PDF
(97K)
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| Reviews | Top |
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Focus on Chromatin Dynamics The establishment and maintenance of lymphocyte identity through gene silencing pp607 - 615 Stephen T Smale doi:10.1038/ni0703-607 Abstract | Full text | PDF
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Focus on Chromatin Dynamics An epigenetic view of helper T cell differentiation pp616 - 623 K Mark Ansel, Dong U Lee
& Anjana Rao doi:10.1038/ni0703-616 Abstract | Full text | PDF
(188K)
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Focus on Chromatin Dynamics Gene segment selection in V(D)J recombination: accessibility and beyond pp624 - 630 Michael S Krangel doi:10.1038/ni0703-624 Abstract | Full text | PDF
(585K)
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Focus on Chromatin Dynamics What role for AID: mutator, or assembler of the immunoglobulin mutasome? pp631 - 638 Claude-Agnès Reynaud, Said Aoufouchi, Ahmad Faili
& Jean-Claude Weill doi:10.1038/ni0703-631 Abstract | Full text | PDF
(314K)
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| News and Views | Top |
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Focus on Chromatin Dynamics Research notes p639 doi:10.1038/ni0703-639 Full text | PDF
(53K)
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| Commentary | Top |
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DNA deamination: not just a trigger for antibody diversification but also a mechanism for defense against retroviruses pp641 - 643 Reuben S Harris, Ann M Sheehy, Heather M Craig, Michael H Malim
& Michael S Neuberger doi:10.1038/ni0703-641 Abstract | Full text | PDF
(87K)
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| Correspondence | Top |
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In search of the CTD p645 Kenneth M. Murphy doi:10.1038/ni0703-645 Full text | PDF
(55K)
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| News and Views | Top |
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More negative feedback? pp647 - 648 Anthony J Coyle
& Jose-Carlos Gutierrez-Ramos doi:10.1038/ni0703-647 Abstract | Full text | PDF
(117K)
See also: Article by Watanabe et al. |
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The problem of plain vanilla peptides pp649 - 650 Mark M Davis doi:10.1038/ni0703-649 Abstract | Full text | PDF
(330K)
See also: Article by Stewart-Jones et al. |
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T-bet: The Toll-bridge to class-switch recombination? pp650 - 652 Ian R Rifkin
& Ann Marshak-Rothstein doi:10.1038/ni0703-650 Abstract | Full text | PDF
(283K)
See also: Article by Liu et al. |
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Intracellular debugging pp652 - 654 Koichi S Kobayashi, Elizabeth E Eynon
& Richard A Flavell doi:10.1038/ni0703-652 Abstract | Full text | PDF
(1,194K)
See also: Article by Chamaillard et al. |
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Research notes p655 doi:10.1038/ni0703-655 Full text | PDF
(54K)
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| Articles | Top |
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A structural basis for immunodominant human T cell receptor recognition pp657 - 663 Guillaume B E Stewart-Jones, Andrew J McMichael, John I Bell, David I Stuart
& E Yvonne Jones Published online: 08 June 2003 | doi:10.1038/ni942 Abstract | Full text | PDF
(633K)
See also: News and Views by Davis |
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The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens pp664 - 669 Jens Lohr, Birgit Knoechel, Shuwei Jiang, Arlene H Sharpe
& Abul K Abbas Published online: 25 May 2003 | doi:10.1038/ni939 Abstract | Full text | PDF
(1,570K)
| Supplementary Information |
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BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 pp670 - 679 Norihiko Watanabe, Maya Gavrieli, John R Sedy, Jianfei Yang, Francesca Fallarino, Susan K Loftin, Michelle A Hurchla, Natalie Zimmerman, Julia Sim, Xingxing Zang, Theresa L Murphy, John H Russell, James P Allison
& Kenneth M Murphy Published online: 08 June 2003 | doi:10.1038/ni944 Abstract | Full text | PDF
(2,347K)
| Supplementary Information See also: News and Views by Coyle & Gutierrez-Ramos |
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Interleukin 7 and T cell receptor signals regulate homeostasis of CD4 memory cells pp680 - 686 Benedict Seddon, Peter Tomlinson
& Rose Zamoyska Published online: 15 June 2003 | doi:10.1038/ni946 Abstract | Full text | PDF
(1,911K)
| Supplementary Information |
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CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells pp687 - 693 Ningshu Liu, Noriko Ohnishi, Lin Ni, Shizuo Akira
& Kevin B Bacon Published online: 25 May 2003 | doi:10.1038/ni941 Abstract | Full text | PDF
(1,224K)
See also: News and Views by Rifkin & Marshak-Rothstein |
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Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity pp694 - 701 Kenji Kabashima, Takahiko Murata, Hiroyuki Tanaka, Toshiyuki Matsuoka, Daiji Sakata, Nobuaki Yoshida, Koko Katagiri, Tatsuo Kinashi, Toshiyuki Tanaka, Masayuki Miyasaka, Hiroichi Nagai, Fumitaka Ushikubi
& Shuh Narumiya Published online: 01 June 2003 | doi:10.1038/ni943 Abstract | Full text | PDF
(1,462K)
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An essential role for NOD1 in host recognition of bacterial peptidoglycan containing diaminopimelic acid pp702 - 707 Mathias Chamaillard, Masahito Hashimoto, Yasuo Horie, Junya Masumoto, Su Qiu, Lisa Saab, Yasunori Ogura, Akiko Kawasaki, Koichi Fukase, Shoichi Kusumoto, Miguel A Valvano, Simon J Foster, Tak W Mak, Gabriel Nuñez
& Naohiro Inohara Published online: 06 June 2003 | doi:10.1038/ni945 Abstract | Full text | PDF
(1,430K)
See also: News and Views by Kobayashi et al. |
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Hematopoietic stem cells engraft in mice with absolute efficiency pp708 - 713 Patricia Benveniste, Claude Cantin, Deborah Hyam
& Norman N. Iscove Published online: 25 May 2003 | doi:10.1038/ni940 Abstract | Full text | PDF
(365K)
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