Richard V. Parry and Carl H. June are at the Abramson Family Cancer Research Institute and Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA. cjune@mail.med.upenn.edu
Calcineurin is negatively regulated by calcipressin 1. Analysis of calcipressin-deficient mice shows that survival of T helper type 1 cells is dependent on calcipressin, demonstrating another function for the regulation of calcineurin activity in T cells.
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