Table of contents


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Editorial

Spot checks p215

doi:10.1038/ni0307-215


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Correspondence

Toll-like receptors and phagosome maturation p217

David G Russell & Robin M Yates

doi:10.1038/ni0307-217a


Reply to "Toll-like receptors and phagosome maturation" pp217 - 218

J Magarian Blander & Ruslan Medzhitov

doi:10.1038/ni0307-217b


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Commentary

CC chemokines and protective immunity: insights gained from mother-to-child transmission of HIV pp219 - 222

Caroline T Tiemessen & Louise Kuhn

doi:10.1038/ni0307-219


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Meeting Report

T cell recognition of lipids: quo vadis? pp223 - 227

Gennaro De Libero, H Robson MacDonald & Paolo Dellabona

doi:10.1038/ni0307-223


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News and Views

Vitamins in control of lymphocyte migration pp229 - 230

Reina E Mebius

doi:10.1038/ni0307-229

See also: Article by Sigmundsdottir et al.


Local sentries for class switching pp230 - 232

Michael McHeyzer-Williams

doi:10.1038/ni0307-230

See also: Article by Xu et al.


Act1-ivating IL-17 inflammation pp232 - 234

Christopher A Hunter

doi:10.1038/ni0307-232

See also: Article by Qian et al.


Claudins provide a breath of fresh Aire pp234 - 236

Georg A Holländer

doi:10.1038/ni0307-234

See also: Article by Hamazaki et al.


Research highlights p237

doi:10.1038/ni0307-237


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Articles

The adaptor Act1 is required for interleukin 17–dependent signaling associated with autoimmune and inflammatory disease pp247 - 256

Youcun Qian, Caini Liu, Justin Hartupee, Cengiz Zubeyir Altuntas, Muhammet Fatih Gulen, Daniel Jane-wit, Jianhua Xiao, Yi Lu, Natalia Giltiay, Jinbo Liu, Tomasz Kordula, Qi-Wei Zhang, Bruce Vallance, Shadi Swaidani, Mark Aronica, Vincent K Tuohy, Thomas Hamilton & Xiaoxia Li

doi:10.1038/ni1439

See also: News and Views by Hunter


Secretory cytotoxic granule maturation and exocytosis require the effector protein hMunc13-4 pp257 - 267

Mickaël M Ménager, Gaël Ménasché, Maryse Romao, Perrine Knapnougel, Chen-Hsuan Ho, Mériem Garfa, Graça Raposo, Jérôme Feldmann, Alain Fischer & Geneviève de Saint Basile

doi:10.1038/ni1431


A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule pp268 - 276

Fleur E Tynan, Hugh H Reid, Lars Kjer-Nielsen, John J Miles, Matthew C J Wilce, Lyudmila Kostenko, Natalie A Borg, Nicholas A Williamson, Travis Beddoe, Anthony W Purcell, Scott R Burrows, James McCluskey & Jamie Rossjohn

doi:10.1038/ni1432




Epithelial cells trigger frontline immunoglobulin class switching through a pathway regulated by the inhibitor SLPI pp294 - 303

Weifeng Xu, Bing He, April Chiu, Amy Chadburn, Meimei Shan, Malwina Buldys, Aihao Ding, Daniel M Knowles, Paul A Santini & Andrea Cerutti

doi:10.1038/ni1434

See also: News and Views by McHeyzer-Williams



Increased IgE-dependent mast cell activation and anaphylactic responses in mice lacking the calcium-activated nonselective cation channel TRPM4 pp312 - 320

Rudi Vennekens, Jenny Olausson, Marcel Meissner, Wilhelm Bloch, Ilka Mathar, Stephan E Philipp, Frank Schmitz, Petra Weissgerber, Bernd Nilius, Veit Flockerzi & Marc Freichel

doi:10.1038/ni1441


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