Focus on Lymphocyte Lineage Specification Factors

The bigger picture - p439

doi:10.1038/ni0507-439

Full Text - The bigger picture | PDF (155 KB) - The bigger picture

Focus on Lymphocyte Lineage Specification Factors

Cell lineage regulators in B and T cell development - pp441 - 444

Ellen V Rothenberg

doi:10.1038/ni1461

Abstract - Cell lineage regulators in B and T cell development | Full Text - Cell lineage regulators in B and T cell development | PDF (160 KB) - Cell lineage regulators in B and T cell development

Focus on Lymphocyte Lineage Specification Factors

Blimp-1 over Budapest - pp445 - 447

Mark M Davis

doi:10.1038/ni0507-445

Full Text - Blimp-1 over Budapest | PDF (303 KB) - Blimp-1 over Budapest

Focus on Lymphocyte Lineage Specification Factors

Trawling for treasure: tales of T-bet - pp448 - 450

Laurie H Glimcher

doi:10.1038/ni0507-448

Full Text - Trawling for treasure: tales of T-bet | PDF (129 KB) - Trawling for treasure: tales of T-bet

Focus on Lymphocyte Lineage Specification Factors

Regulation of lymphocyte development by Notch signaling - pp451 - 456

Kenji Tanigaki & Tasuku Honjo

doi:10.1038/ni1453

Abstract - Regulation of lymphocyte development by Notch signaling | Full Text - Regulation of lymphocyte development by Notch signaling | PDF (423 KB) - Regulation of lymphocyte development by Notch signaling

Focus on Lymphocyte Lineage Specification Factors

Foxp3 in control of the regulatory T cell lineage - pp457 - 462

Ye Zheng & Alexander Y Rudensky

doi:10.1038/ni1455

Abstract - Foxp3 in control of the regulatory T cell lineage | Full Text - Foxp3 in control of the regulatory T cell lineage | PDF (450 KB) - Foxp3 in control of the regulatory T cell lineage

Focus on Lymphocyte Lineage Specification Factors

Pax5: the guardian of B cell identity and function - pp463 - 470

César Cobaleda, Alexandra Schebesta, Alessio Delogu & Meinrad Busslinger

doi:10.1038/ni1454

Abstract - Pax5: the guardian of B cell identity and function | Full Text - Pax5: the guardian of B cell identity and function | PDF (635 KB) - Pax5: the guardian of B cell identity and function

Focus on Lymphocyte Lineage Specification Factors

Research Highlights - p471

doi:10.1038/ni0507-471

Full Text - Research Highlights | PDF (85 KB) - Research Highlights

Incomplete screening? - p473

Ira Mellman

doi:10.1038/ni0507-473

Full Text - Incomplete screening? | PDF (73 KB) - Incomplete screening?

TLR9 and DNA 'feel' RAGE - pp475 - 477

Arthur M Krieg

doi:10.1038/ni0507-475

Full Text - TLR9 and DNA 'feel' RAGE | PDF (523 KB) - TLR9 and DNA 'feel' RAGE

See also: Article by Tian et al.

Smads keep TABs on inflammation - pp477 - 478

Rashu B Seth & Zhijian J Chen

doi:10.1038/ni0507-477

Full Text - Smads keep TABs on inflammation | PDF (613 KB) - Smads keep TABs on inflammation

See also: Article by Hong et al.

Epithelial NF-B maintains host gut microflora homeostasis - pp479 - 481

Yinon Ben-Neriah & Marc Schmidt-Supprian

doi:10.1038/ni0507-479

Full Text - Epithelial NF-B maintains host gut microflora homeostasis | PDF (311 KB) - Epithelial NF-B maintains host gut microflora homeostasis

Giving B cell tolerance the 'TSLiP' - pp481 - 483

David Allman & Dan Northrup

doi:10.1038/ni0507-481

Full Text - Giving B cell tolerance the 'TSLiP' | PDF (3,572 KB) - Giving B cell tolerance the 'TSLiP'

See also: Article by Astrakhan et al.

Research Highlights - p485

doi:10.1038/ni0507-485

Full Text - Research Highlights | PDF (86 KB) - Research Highlights

Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE - pp487 - 496

Jane Tian, Ana Maria Avalos, Su-Yau Mao, Bo Chen, Kannaki Senthil, Herren Wu, Peggy Parroche, Stacey Drabic, Douglas Golenbock, Cherilyn Sirois, Jing Hua, Ling Ling An, Laurent Audoly, Greg La Rosa, Angelika Bierhaus, Peter Naworth, Ann Marshak-Rothstein, Mary K Crow, Katherine A Fitzgerald, Eicke Latz, Peter A Kiener & Anthony J Coyle

doi:10.1038/ni1457

Abstract - Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE | Full Text - Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE | PDF (386 KB) - Toll-like receptor 9–dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGE | Supplementary information

See also: News and Views by Krieg

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses - pp497 - 503

Annick Mayor, Fabio Martinon, Thibaut De Smedt, Virginie Pétrilli & Jürg Tschopp

doi:10.1038/ni1459

Abstract - A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses | Full Text - A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses | PDF (308 KB) - A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses | Supplementary information

Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2 - pp504 - 513

Suntaek Hong, Seunghwan Lim, Allen G Li, Chan Lee, Youn Sook Lee, Eun-Kyung Lee, Seok Hee Park, Xiao-Jing Wang & Seong-Jin Kim

doi:10.1038/ni1451

Abstract - Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2 | Full Text - Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2 | PDF (561 KB) - Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2 | Supplementary information

See also: News and Views by Seth & Chen

Production of Ins(1,3,4,5)P₄ mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation - pp514 - 521

Andrew T Miller, Mark Sandberg, Yina H Huang, Michael Young, Susan Sutton, Karsten Sauer & Michael P Cooke

doi:10.1038/ni1458

Abstract - Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation | Full Text - Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation | PDF (460 KB) - Production of Ins(1,3,4,5)P4 mediated by the kinase Itpkb inhibits store-operated calcium channels and regulates B cell selection and activation | Supplementary information

Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development - pp522 - 531

Alexander Astrakhan, Miyuki Omori, Thuc Nguyen, Shirly Becker-Herman, Masanori Iseki, Theingi Aye, Kelly Hudkins, James Dooley, Andrew Farr, Charles E Alpers, Steven F Ziegler & David J Rawlings

doi:10.1038/ni1452

Abstract - Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development | Full Text - Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development | PDF (789 KB) - Local increase in thymic stromal lymphopoietin induces systemic alterations in B cell development | Supplementary information

See also: News and Views by Allman & Northrup

Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs - pp532 - 539

Krystle M Veerman, Michael J Williams, Kenji Uchimura, Mark S Singer, Jasmeen S Merzaban, Silvia Naus, Douglas A Carlow, Philip Owen, Jesús Rivera-Nieves, Steven D Rosen & Hermann J Ziltener

doi:10.1038/ni1456

Abstract - Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs | Full Text - Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs | PDF (633 KB) - Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs | Supplementary information