News and Views
Nature Immunology 9, 1095 - 1096 (2008)
doi:10.1038/ni1008-1095
Putting ThPOK in place
J Jeremiah Bell1 & Avinash Bhandoola1
-
J. Jeremiah Bell and Avinash Bhandoola are in the Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA.
e-mail: bhandooa@mail.med.upenn.edu
Abstract
ThPOK is necessary for the differentiation of CD4+ helper T cells. Three new studies indicate that, unexpectedly, ThPOK is required only after initial specification to the CD4+ lineage.
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Switching sides: transcriptional control of CD4 thymocyte lineage commitmentNature Immunology News and Views (01 Apr 2005)
Immunology Guide for a cell-fate decisionNature News and Views (24 Feb 2005)
See all 5 matches for News And ViewsRESEARCH
BOB.1/OBF.1 controls the balance of TH1 and TH2 immune responsesThe EMBO Journal Article (11 Jul 2007)
Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4 + T cellsNature Immunology Article (01 Oct 2008)
See all 12 matches for Research