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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Guide to authors Online submission For referees Free online issue Contact the journal Subscribe Advertising work@npg Reprints and permissions About this site For librarians   NPG Resources Nature Nature Reviews Nature Immunology Nature Cell Biology Nature Genetics news@nature.com Nature Conferences Dissect Medicine NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications Review Nature Medicine  11, S45 - S53 (2005) Published online: ; | doi:10.1038/nm1213 Mucosal immunity and vaccines Jan Holmgren1 & Cecil Czerkinsky2 1  Department of Medical Microbiology & Immunology and Göteborg University Vaccine Research Institute (GUVAX), Göteborg University, SE-405 30 Göteborg, Sweden. 2  INSERM Unité 721, Faculté de Médicine−Pasteur, F-06107 Nice Cedex 02, France. Correspondence should be addressed to Jan Holmgren jan.holmgren@microbio.gu.seThere is currently great interest in developing mucosal vaccines against a variety of microbial pathogens. Mucosally induced tolerance also seems to be a promising form of immunomodulation for treating certain autoimmune diseases and allergies. Here we review the properties of the mucosal immune system and discuss advances in the development of mucosal vaccines for protection against infections and for treatment of various inflammatory disorders. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated. NEWS AND VIEWS Slaying the Hydra all at once or head by head? Nature Medicine News and Views (01 May 1998) Pharmaceutical foodstuffs?oral immunization with transgenic plants Nature Medicine News and Views (01 May 1998) See all 4 matches for News And Views RESEARCH The role of ADP-ribosylation and GM1-binding activity in the mucosal immunogenicity and adjuvanticity of the Escherichia coli heat-labile enterotoxin and Vibrio cholerae cholera toxin Immunology and Cell Biology Original Article A plant-based multicomponent vaccine protects mice from enteric diseases Nature Biotechnology Research (01 Jun 2001) See all 13 matches for Research  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Open Innovation Challenges Novel Approaches to Protecting Maize from Insect Damage Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re... Single-cell Analysis Platform Deadline: Dec 02 2009 Reward: $5,000 USD This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is... More Challenges Powered by: nature jobs Team Leader Eli Lilly Surrey, United kindom Sr. Scientific Manager / Chief Scientific Manager- Discovery Metabolism and Pharmacokinetics (MAP) Syngene International Bangalore, Karnataka 560099 India More science jobs Post a job for free Figures & Tables Export citation Search buyers guide:   ADVERTISEMENT

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