Table of contents
December 2007, Volume 13 No 12 pp1389-1521
About the coverEditorials
Cold shower for AIDS vaccines - pp1389 - 1390
doi:10.1038/nm1207-1389
Abstract - | Full Text - Cold shower for AIDS vaccines | PDF (105 KB) - Cold shower for AIDS vaccines
Frontiers of Clinical Investigation 2007 - p1390
doi:10.1038/nm1207-1390
Abstract - | Full Text - Frontiers of Clinical Investigation 2007 | PDF (53 KB) - Frontiers of Clinical Investigation 2007
News
BBC apologizes for airing AIDS 'denialist' documentary - p1391
Virginia Hughes
doi:10.1038/nm1207-1391
Full Text - BBC apologizes for airing AIDS 'denialist' documentary | PDF (349 KB) - BBC apologizes for airing AIDS 'denialist' documentary
Spat over firing threatens medical school at US-Mexico border - p1392
Brendan Borrell
doi:10.1038/nm1207-1392
Full Text - Spat over firing threatens medical school at US-Mexico border | PDF (233 KB) - Spat over firing threatens medical school at US-Mexico border
Institutional changes may mean more resources for Indian scientists - p1393
T. V. Padma
doi:10.1038/nm1207-1393
Full Text - Institutional changes may mean more resources for Indian scientists | PDF (274 KB) - Institutional changes may mean more resources for Indian scientists
Polio eradication campaign copes with unusual outbreak - p1394
Cassandra Willyard
doi:10.1038/nm1207-1394
Full Text - Polio eradication campaign copes with unusual outbreak | PDF (380 KB) - Polio eradication campaign copes with unusual outbreak
Profile: Hugh Herr - p1395
Cassandra Willyard
doi:10.1038/nm1207-1395
Abstract - | Full Text - Profile: Hugh Herr | PDF (137 KB) - Profile: Hugh Herr
News in brief - pp1396 - 1397
doi:10.1038/nm1207-1396
Abstract - | Full Text - News in brief | PDF (445 KB) - News in brief
2007 in review
Biomedicine in the headlines - p1399
doi:10.1038/nm1207-1399
Abstract - | Full Text - Biomedicine in the headlines | PDF (322 KB) - Biomedicine in the headlines
An eventful year for the FDA - p1400
doi:10.1038/nm1207-1400
Full Text - An eventful year for the FDA | PDF (386 KB) - An eventful year for the FDA
Notable advances - p1401
doi:10.1038/nm1207-1401
Abstract - | Full Text - Notable advances | PDF (369 KB) - Notable advances
Timeline of events - p1402
doi:10.1038/nm1207-1402
Abstract - | Full Text - Timeline of events | PDF (648 KB) - Timeline of events
Looking back - p1403
doi:10.1038/nm1207-1403
Abstract - | Full Text - Looking back | PDF (385 KB) - Looking back
Correspondence
Poring over pores:
-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia - pp1405 - 1406
Juliane Bubeck Wardenburg, Taeok Bae, Michael Otto, Frank R DeLeo & Olaf Schneewind
doi:10.1038/nm1207-1405
Full Text - Poring over pores:
-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia | PDF (435 KB) - Poring over pores:
-hemolysin and Panton-Valentine leukocidin in Staphylococcus aureus pneumonia | Supplementary information
See also: News and Views by Lowy | Letter by Wang et al.
Book Review
The stem cell controversy - p1407
Clive N Svendsen reviews Renewing the stuff of life: Stem cells, ethics, and public policy by Cynthia B Cohen
doi:10.1038/nm1207-1407
Full Text - The stem cell controversy | PDF (92 KB) - The stem cell controversy
News and Views
Sensitive cilia set up the kidney - pp1409 - 1411
Emily Kim & Gerd Walz
doi:10.1038/nm1207-1409
Abstract - | Full Text - Sensitive cilia set up the kidney | PDF (596 KB) - Sensitive cilia set up the kidney
See also: Letter by Piontek et al.
Building the bionic T cell - pp1411 - 1413
Drew M Pardoll
doi:10.1038/nm1207-1411
Abstract - | Full Text - Building the bionic T cell | PDF (307 KB) - Building the bionic T cell
See also: Article by Stephan et al.
Dying T cells trigger autoimmunity in HIV - pp1413 - 1415
Sarah Rowland-Jones & Tao Dong
doi:10.1038/nm1207-1413
Abstract - | Full Text - Dying T cells trigger autoimmunity in HIV | PDF (499 KB) - Dying T cells trigger autoimmunity in HIV
See also: Article by Rawson et al.
Putting the heat on cancer - pp1415 - 1417
Paul Workman & Emmanuel de Billy
doi:10.1038/nm1207-1415
Abstract - | Full Text - Putting the heat on cancer | PDF (1,278 KB) - Putting the heat on cancer
Incapacitating the immune system in cystic fibrosis - pp1417 - 1418
Ian Sabroe & Moira K B Whyte
doi:10.1038/nm1207-1417
Abstract - | Full Text - Incapacitating the immune system in cystic fibrosis | PDF (954 KB) - Incapacitating the immune system in cystic fibrosis
See also: Article by Hartl et al.
Secrets of a superbug - pp1418 - 1420
Franklin D Lowy
doi:10.1038/nm1207-1418
Abstract - | Full Text - Secrets of a superbug | PDF (291 KB) - Secrets of a superbug
See also: Correspondence by Bubeck Wardenburg et al. | Letter by Wang et al.
Research Highlights - pp1421 - 1422
doi:10.1038/nm1207-1421
Full Text - Research Highlights | PDF (308 KB) - Research Highlights
Articles
Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease - pp1423 - 1430
Dominik Hartl, Philipp Latzin, Peter Hordijk, Veronica Marcos, Carsten Rudolph, Markus Woischnik, Susanne Krauss-Etschmann, Barbara Koller, Dietrich Reinhardt, Adelbert A Roscher, Dirk Roos & Matthias Griese
doi:10.1038/nm1690
Abstract - | Full Text - Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease | PDF (367 KB) - Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease | Supplementary information
See also: News and Views by Sabroe & Whyte
Cross-presentation of caspase-cleaved apoptotic self antigens in HIV infection - pp1431 - 1439
Pisana Moroni Rawson, Caroline Molette, Melissa Videtta, Laura Altieri, Debora Franceschini, Tiziana Donato, Luigi Finocchi, Antonella Propato, Marino Paroli, Francesca Meloni, Claudio M Mastroianni, Gabriella d'Ettorre, John Sidney, Alessandro Sette & Vincenzo Barnaba
doi:10.1038/nm1679
Abstract - | Full Text - Cross-presentation of caspase-cleaved apoptotic self antigens in HIV infection | PDF (430 KB) - Cross-presentation of caspase-cleaved apoptotic self antigens in HIV infection | Supplementary information
See also: News and Views by Rowland-Jones & Dong
T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection - pp1440 - 1449
Matthias T Stephan, Vladimir Ponomarev, Renier J Brentjens, Alex H Chang, Konstantin V Dobrenkov, Glenn Heller & Michel Sadelain
doi:10.1038/nm1676
Abstract - | Full Text - T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection | PDF (977 KB) - T cell–encoded CD80 and 4-1BBL induce auto- and transcostimulation, resulting in potent tumor rejection | Supplementary information
See also: News and Views by Pardoll
A pivotal role for galectin-1 in fetomaternal tolerance - pp1450 - 1457
Sandra M Blois, Juan M Ilarregui, Mareike Tometten, Mariana Garcia, Arif S Orsal, Rosalia Cordo-Russo, Marta A Toscano, Germán A Bianco, Peter Kobelt, Bori Handjiski, Irene Tirado, Udo R Markert, Burghard F Klapp, Francoise Poirier, Julia Szekeres-Bartho, Gabriel A Rabinovich & Petra C Arck
doi:10.1038/nm1680
Abstract - | Full Text - A pivotal role for galectin-1 in fetomaternal tolerance | PDF (435 KB) - A pivotal role for galectin-1 in fetomaternal tolerance | Supplementary information
Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation - pp1458 - 1466
Tuomas Tammela, Anne Saaristo, Tanja Holopainen, Johannes Lyytikkä, Anna Kotronen, Miia Pitkonen, Usama Abo-Ramadan, Seppo Ylä-Herttuala, Tatiana V Petrova & Kari Alitalo
doi:10.1038/nm1689
Abstract - | Full Text - Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation | PDF (941 KB) - Therapeutic differentiation and maturation of lymphatic vessels after lymph node dissection and transplantation | Supplementary information
Pim-1 regulates cardiomyocyte survival downstream of Akt - pp1467 - 1475
John A Muraski, Marcello Rota, Yu Misao, Jenna Fransioli, Christopher Cottage, Natalie Gude, Grazia Esposito, Francesca Delucchi, Michael Arcarese, Roberto Alvarez, Sailay Siddiqi, Gregory N Emmanuel, Weitao Wu, Kimberlee Fischer, Joshua J Martindale, Christopher C Glembotski, Annarosa Leri, Jan Kajstura, Nancy Magnuson, Anton Berns, Remus M Beretta, Steven R Houser, Erik M Schaefer, Piero Anversa & Mark A Sussman
doi:10.1038/nm1671
Abstract - | Full Text - Pim-1 regulates cardiomyocyte survival downstream of Akt | PDF (658 KB) - Pim-1 regulates cardiomyocyte survival downstream of Akt | Supplementary information
Antidepressant actions of the exercise-regulated gene VGF - pp1476 - 1482
Joshua G Hunsberger, Samuel S Newton, Alicia H Bennett, Catharine H Duman, David S Russell, Stephen R Salton & Ronald S Duman
doi:10.1038/nm1669
Abstract - | Full Text - Antidepressant actions of the exercise-regulated gene VGF | PDF (401 KB) - Antidepressant actions of the exercise-regulated gene VGF | Supplementary information
Letters
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system - pp1483 - 1489
Manuel A Friese, Matthew J Craner, Ruth Etzensperger, Sandra Vergo, John A Wemmie, Michael J Welsh, Angela Vincent & Lars Fugger
doi:10.1038/nm1668
First paragraph - | Full Text - Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system | PDF (408 KB) - Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system | Supplementary information
A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 - pp1490 - 1495
Klaus Piontek, Luis F Menezes, Miguel A Garcia-Gonzalez, David L Huso & Gregory G Germino
doi:10.1038/nm1675
First paragraph - | Full Text - A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 | PDF (713 KB) - A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1 | Supplementary information
See also: News and Views by Kim & Walz
PPAR-
regulates osteoclastogenesis in mice - pp1496 - 1503
Yihong Wan, Ling-Wa Chong & Ronald M Evans
doi:10.1038/nm1672
First paragraph - | Full Text - PPAR-
regulates osteoclastogenesis in mice | PDF (818 KB) - PPAR-
regulates osteoclastogenesis in mice | Supplementary information
The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation - pp1504 - 1509
Yien Che Tsai, Arnulfo Mendoza, Jennifer M Mariano, Ming Zhou, Zlatka Kostova, Bo Chen, Timothy Veenstra, Stephen M Hewitt, Lee J Helman, Chand Khanna & Allan M Weissman
doi:10.1038/nm1686
First paragraph - | Full Text - The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation | PDF (380 KB) - The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation | Supplementary information
Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA - pp1510 - 1514
Rong Wang, Kevin R Braughton, Dorothee Kretschmer, Thanh-Huy L Bach, Shu Y Queck, Min Li, Adam D Kennedy, David W Dorward, Seymour J Klebanoff, Andreas Peschel, Frank R DeLeo & Michael Otto
doi:10.1038/nm1656
First paragraph - | Full Text - Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA | PDF (423 KB) - Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA | Supplementary information
See also: Correspondence by Bubeck Wardenburg et al. | News and Views by Lowy
Technical Report
In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice - pp1515 - 1520
Sheetal Gandotra, Dirk Schnappinger, Mercedes Monteleone, Wolfgang Hillen & Sabine Ehrt
doi:10.1038/nm1683
Abstract - | Full Text - In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice | PDF (284 KB) - In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice | Supplementary information
Erratum
Erratum: Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy - p1521
Sam E Day, Mikko I Kettunen, Ferdia A Gallagher, De-En Hu, Mathilde Lerche, Jan Wolber, Klaes Golman, Jan Henrik Ardenkjaer-Larsen & Kevin M Brindle
doi:10.1038/nm1207-1521
Full Text - Erratum: Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy | PDF (57 KB) - Erratum: Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy


