Access
To read this story in full you will need to login or make a payment (see right).
News
Nature Medicine 13, 227 (2007)
Published online: 28 February 2007 | doi:10.1038/nm0307-227
Trials race rashly ahead for regulatory immune cells
Douglas Braaten1
- New York
Abstract
The cells could be an effective treatment for people with autoimmune diseases.
Horror autotoxicus: lethal, ravaging autoimmunity—a terrifying fate that would await us all, were it not for the constant surveillance of a relatively small number of immune cells, whose task it is to keep the rest of the immune system under tight control.That is the remarkable implication of a study, published in February, showing that in adult mice, depleting regulatory T cells, or 'Tregs', rapidly causes severe wasting disease, massive inflammation and death (Nat. Immunol. 8, 191–197; 2007
To read this story in full you will need to login or make a payment (see right).
