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Nature Medicine 13, 290-294 (1 March 2007) | doi:10.1038/nm0307-290;

Challenges in tuberculosis drug research and development

Ann M Ginsberg & Melvin Spigelman

The present decade has seen a reawakening of tuberculosis (TB) drug research and development (R&D), spurred on by an urgent need to stem the tide of the disease globally and develop new, more effective treatments against drug-sensitive and resistant strains. As a result, there are now seven products in clinical development and the largest pipeline of early-stage projects and compounds in history.

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