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Commentary
Nature Medicine 13, 295 - 298 (2007)
doi:10.1038/nm0307-295
From magic bullets back to the Magic Mountain: the rise of extensively drug-resistant tuberculosis
Susan E Dorman1 & Richard E Chaisson1
- The authors are at the Center for Tuberculosis Research, 1550 Orleans Street, Room 1M.08, Johns Hopkins University, Baltimore, Maryland 21231, USA. e-mail: rchaiss@jhmi.edu
Extensively drug-resistant tuberculosis (XDR-TB) occurs where health systems have been historically weak; it lays bare the reality of TB as a serious public health problem, especially in areas of high HIV prevalence, and reinforces the need for effective TB control strategies that are coordinated with HIV control. The problem of XDR-TB in high HIV prevalence settings challenges all aspects of the public health and health-care systems, and will require an integrated approach.
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