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Nature Medicine 13, 404 - 406 (2007)
doi:10.1038/nm0407-404

Providing AID to p53 mutagenesis

Shigeo Takaishi1 & Timothy C Wang1

  1. The authors are in the Division of Digestive and Liver Diseases, Department of Medicine, Columbia University, College of Physicians & Surgeons, Irving Cancer Research Center, 1130 St. Nicholas Avenue, Room 925, New York, New York 10032, USA. e-mail: tcw21@columbia.edu


Activation-induced cytidine deaminase (AID), which mediates antibody diversification, is now implicated as an inducer of p53 mutagenesis in cancer cells (pages 470–476).

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