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Nature Medicine 4, 1122 - 1123 (1998)
doi:10.1038/2617

New clues to the emergence of flu pandemics

Eric C.J. Claas1,2 & Albert D.M.E. Osterhaus1

  1. Dept. of Virology and WHO National Influenza Centre, Erasmus University Rotterdam, P.O. Box 1738, 3000 DR Rotterdam
  2. Dept. of Virology, CKVL, Leiden University Medical Center, P.O Box 9600, 2300 RCLeiden The Netherlandse-mail: Claas@virology.azl.nl


The discovery of a new virulence mechanism in an influenza A (H1N1) virus may help to explain how flu viruses acquire virulence and why the 1918 flu pandemic was so devastating.


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