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Nature Medicine
ISSUE
April 2003, Volume 9 No 4
Editorial
Letters to Editor
News
Commentary
Book Reviews
News and Views
Articles
New Technology
Errata
Corrigenda
About the cover
Editorial Top
Days of Molecular Medicine '03 p365
doi:10.1038/nm0403-365
Full text | PDF (43K)
Letters to Editor Top
Safety of retroviral gene marking with a truncated NGF receptor pp367 - 369
C. Bonini, M. Grez, C. Traversari, F. Ciceri, S. Marktel, G. Ferrari, M. Dinauer, M. Sadat, A. Aiuti, S. Deola, M. Radrizzani, A. Hagenbeek, J. Apperley, S. Ebeling, A. Martens, H.J. Kolb, M. Weber, F. Lotti, A. Grande, E. Weissinger, J.A. Bueren, M. Lamana, J.H.F. Falkenburg, M.H.M. Heemskerk, T. Austin, S. Kornblau, F. Marini, C. Benati, Z. Magnani, S. Cazzaniga, S. Toma, C. Gallo-Stampino, M. Introna, S. Slavin, P.D. Greenberg, M. Bregni, F. Mavilio & C. Bordignon
doi:10.1038/nm0403-367
Full text | PDF (89K)  | Supplementary Information
Effect of TERT over-expression on the long-term transplantation capacity of hematopoietic stem cells pp369 - 371
Richard C. Allsopp, Gregg B. Morin, James W. Horner, Ronald DePinho, Calvin B. Harley & Irving L. Weissman
doi:10.1038/nm0403-369
Full text | PDF (630K)
Tissue plasminogen activator and NMDA receptor cleavage pp371 - 372
Tomasz Matys & Sidney Strickland
doi:10.1038/nm0403-371
Full text | PDF (498K)
Reply to "Tissue plasminogen activator and NMDA receptor cleavage" pp372 - 373
Denis Vivien, Monica Fernandez Monréal, Olivier Nicole & Alain Buisson
doi:10.1038/nm0403-372
Full text | PDF (117K)
News Top
Looming flu pandemic has experts crying fowl p375
Julie Clayton
doi:10.1038/nm0403-375
Full text | PDF (443K)
AIDSVAX flop leaves vaccine field unscathed p376
Tinker Ready
doi:10.1038/nm0403-376a
Full text | PDF (68K)
Skeptical scientists skewer VaxGen statistics p376
Myrna E. Watanabe
doi:10.1038/nm0403-376b
Full text | PDF (68K)
India sets its sights on global health care market p377
K.S. Jayaraman
doi:10.1038/nm0403-377a
Full text | PDF (99K)
'Fools' rush in where genome giants fear to tread p377
Charlotte Schubert
doi:10.1038/nm0403-377b
Full text | PDF (99K)
Ambitious researchers take awkward first steps to a Euro-NIH p378
Laura Spinney
doi:10.1038/nm0403-378a
Full text | PDF (144K)
Spain strives for its own 'excellence' p378
Xavier Bosch
doi:10.1038/nm0403-378b
Full text | PDF (145K)
Troubled times force old pharma to learn new tricks p379
Apoorva Mandavilli
doi:10.1038/nm0403-379a
Full text | PDF (200K)
UK's National Health Service joins publishing free-for-all p379
Stacie Grossman
doi:10.1038/nm0403-379b
Full text | PDF (200K)
Dennis Burton p380
Apoorva Mandavilli
doi:10.1038/nm0403-380
Abstract | Full text | PDF (106K)
Art imitates life p381
doi:10.1038/nm0403-381
Full text | PDF (1,059K)
Commentary Top
Chromosomal translocation products engender new intracellular therapeutic technologies pp383 - 386
Terence H. Rabbitts & Martin R. Stocks
doi:10.1038/nm0403-383
Abstract | Full text | PDF (575K)
Book Reviews Top
Watson and DNA: Making a Scientific Revolution p387
Reviewed by: Judah Folkman
doi:10.1038/nm0403-387
Full text | PDF (195K)
Engendering International Health: The Challenge of Equity p388
Reviewed by: M. Omar Rahman
doi:10.1038/nm0403-388
Full text | PDF (113K)
News and Views Top
Alzheimer disease's double-edged vaccine pp389 - 390
S. M. Greenberg, B. J. Bacskai & B. T. Hyman
Published online: 17 March 2003 | doi:10.1038/nm847
Abstract | Full text | PDF (437K)
See also: Article by Nicoll et al.
Is resistance futile? pp390 - 392
Allison McGeer & Donald E. Low
doi:10.1038/nm0403-390
Abstract | Full text | PDF (441K)
See also: Article by McCormick et al.
Breaking away from the breast p392
Charlotte Schubert
doi:10.1038/nm0403-392
Full text | PDF (230K)
HIV-1: nature's master of disguise pp393 - 394
John R. Mascola & David C. Montefiori
doi:10.1038/nm0403-393
Abstract | Full text | PDF (222K)
Bad bones, grey hair, one mutation pp395 - 396
Brendan F. Boyce
doi:10.1038/nm0403-395
Abstract | Full text | PDF (740K)
See also: Article by Chalhoub et al.
Meddling in macular degeneration p396
Charlotte Schubert
doi:10.1038/nm0403-396
Full text | PDF (432K)
Research news p397
Charlotte Schubert
doi:10.1038/nm0403-397
Full text | PDF (220K)
Articles Top
Grey-lethal mutation induces severe malignant autosomal recessive osteopetrosis in mouse and human pp399 - 406
Nader Chalhoub, Nadia Benachenhou, Venkatesh Rajapurohitam, Monica Pata, Mathieu Ferron, Annalisa Frattini, Anna Villa & Jean Vacher
Published online: 10 March 2003 | doi:10.1038/nm842
Abstract | Full text | PDF (527K)
See also: News and Views by Boyce
A novel function for tissue inhibitor of metalloproteinases-3 (TIMP3): inhibition of angiogenesis by blockage of VEGF binding to VEGF receptor-2 pp407 - 415
Jian Hua Qi, Quteba Ebrahem, Nina Moore, Gillian Murphy, Lena Claesson-Welsh, Mark Bond, Andrew Baker & Bela Anand-Apte
Published online: 24 March 2003 | doi:10.1038/nm846
Abstract | Full text | PDF (2,834K)
Predicting hepatitis B virus−positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning pp416 - 423
Qing-Hai Ye, Lun-Xiu Qin, Marshonna Forgues, Ping He, Jin Woo Kim, Amy C. Peng, Richard Simon, Yan Li, Ana I. Robles, Yidong Chen, Zeng-Chen Ma, Zhi-Quan Wu, Sheng-Long Ye, Yin-Kun Liu, Zhao-You Tang & Xin Wei Wang
Published online: 17 March 2003 | doi:10.1038/nm843
Abstract | Full text | PDF (2,751K)  | Supplementary Information
Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States pp424 - 430
Althea W. McCormick, Cynthia G. Whitney, Monica M. Farley, Ruth Lynfield, Lee H. Harrison, Nancy M. Bennett, William Schaffner, Arthur Reingold, James Hadler, Paul Cieslak, Matthew H. Samore & Marc Lipsitch
Published online: 10 March 2003 | doi:10.1038/nm839
Abstract | Full text | PDF (117K)
See also: News and Views by McGeer & Low
F(ab)'2-mediated neutralization of C3a and C5a anaphylatoxins: a novel effector function of immunoglobulins pp431 - 438
Milan Basta, Fredric Van Goor, Stefano Luccioli, Eric M. Billings, Alexander O. Vortmeyer, Lajos Baranyi, Janos Szebeni, Carl R. Alving, Michael C. Carroll, Ira Berkower, Stanko S. Stojilkovic & Dean D. Metcalfe
Published online: 03 March 2003 | doi:10.1038/nm836
Abstract | Full text | PDF (1,102K)
Identification and isolation of multipotential neural progenitor cells from the subcortical white matter of the adult human brain pp439 - 447
Marta C. Nunes, Neeta Singh Roy, H. Michael Keyoung, Robert R. Goodman, Guy McKhann II, Li Jiang, Jian Kang, Maiken Nedergaard & Steven A. Goldman
Published online: 10 March 2003 | doi:10.1038/nm837
Abstract | Full text | PDF (2,804K)  | Supplementary Information
Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report pp448 - 452
James A.R. Nicoll, David Wilkinson, Clive Holmes, Phil Steart, Hannah Markham & Roy O. Weller
Published online: 17 March 2003 | doi:10.1038/nm840
Abstract | Full text | PDF (1,021K)
See also: News and Views by Greenberg et al.
Adult mouse astrocytes degrade amyloid-beta in vitro and in situ pp453 - 457
Tony Wyss-Coray, John D. Loike, Thomas C. Brionne, Emily Lu, Roman Anankov, Fengrong Yan, Samuel C. Silverstein & Jens Husemann
Published online: 03 March 2003 | doi:10.1038/nm838
Abstract | Full text | PDF (1,334K)
Alternatively spliced human tissue factor: a circulating, soluble, thrombogenic protein pp458 - 462
Vladimir Y. Bogdanov, Viji Balasubramanian, James Hathcock, Oana Vele, Mark Lieb & Yale Nemerson
Published online: 24 March 2003 | doi:10.1038/nm841
Abstract | Full text | PDF (661K)
Clonality analysis after retroviral-mediated gene transfer to CD34+ cells from the cord blood of ADA-deficient SCID neonates pp463 - 468
Manfred Schmidt, Denise A. Carbonaro, Carsten Speckmann, Manuela Wissler, John Bohnsack, Melissa Elder, Bruce J. Aronow, Jan A. Nolta, Donald B. Kohn & Christof von Kalle
Published online: 17 March 2003 | doi:10.1038/nm844
Abstract | Full text | PDF (698K)
New Technology Top
Detection of virus-specific T cells and CD8+ T-cell epitopes by acquisition of peptide−HLA-GFP complexes: analysis of T-cell phenotype and function in chronic viral infections pp469 - 475
Utano Tomaru, Yoshihisa Yamano, Masahiro Nagai, Dragan Maric, Previn T.P. Kaumaya, William Biddison & Steven Jacobson
Published online: 24 March 2003 | doi:10.1038/nm845
Abstract | Full text | PDF (785K)
On the market p476
doi:10.1038/nm0403-476
Full text | PDF (275K)
Errata Top
Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells p477
Sharof M. Tugizov, Jennifer W. Berline & Joel M. Palefsky
doi:10.1038/nm0403-477a
Full text | PDF (55K)
Toll-like receptor-4 (TLR4) signaling augments chemokine-induced neutrophil migration by modulating cell surface expression of chemokine receptors p477
Jie Fan & Asrar B. Malik
doi:10.1038/nm0403-477b
Full text | PDF (55K)
Corrigenda Top
Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics p477
Joanne T. Brindle, Henrik Antti, Elaine Holmes, George Tranter, Jeremy K. Nicholson, Hugh W.L. Bethell, Sarah Clarke, Peter M. Schofield, Elaine McKilligin, David E. Mosedale & David J. Grainger
doi:10.1038/nm0403-477c
Full text | PDF (55K)
Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells p477
Sharof M. Tugizov, Jennifer W. Berline & Joel M. Palefsky
doi:10.1038/nm0403-477d
Full text | PDF (55K)
  Top
 
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ISSN: 1078-8956
EISSN: 1546-170X
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