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| Editorial | Top |
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Proteomics' framework for success? pp1 - 2 doi:10.1038/nmeth0107-1 Abstract | Full text | PDF
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| Correspondence | Top |
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BRET analysis of GPCR oligomerization: newer does not mean better pp3 - 4 Michel Bouvier, Nikolaus Heveker, Ralf Jockers, Stefano Marullo & Graeme Milligan doi:10.1038/nmeth0107-3 Full text | PDF
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BRET analysis of GPCR oligomerization: newer does not mean better p4 John R James & Simon J Davis doi:10.1038/nmeth0107-4 Full text | PDF
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| Research Highlights | Top |
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Lipids under scrutiny p7 Nicole Rusk doi:10.1038/nmeth0107-7 Abstract | Full text | PDF
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Good enhancer hunting pp8 - 9 Jesse Potash doi:10.1038/nmeth0107-8a Abstract | Full text | PDF
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Annotating the unannotated pp8 - 9 Allison Doerr doi:10.1038/nmeth0107-8b Abstract | Full text | PDF
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News in brief p9 doi:10.1038/nmeth0107-9 Full text | PDF
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A prince for Sleeping Beauty p10 Nicole Rusk doi:10.1038/nmeth0107-10 Abstract | Full text | PDF
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| Commentary | Top |
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ProteomeBinders: planning a European resource of affinity reagents for analysis of the human proteome pp13 - 17 Michael J Taussig, Oda Stoevesandt, Carl A K Borrebaeck, Andrew R Bradbury, Dolores Cahill, Christian Cambillau, Antoine de Daruvar, Stefan Dübel, Jutta Eichler, Ronald Frank, Toby J Gibson, David Gloriam, Larry Gold, Friedrich W Herberg, Henning Hermjakob, Jörg D Hoheisel, Thomas O Joos, Olli Kallioniemi, Manfred Koegl, Zoltán Konthur, Bernhard Korn, Elisabeth Kremmer, Sylvia Krobitsch, Ulf Landegren, Silvère van der Maarel, John McCafferty, Serge Muyldermans, Per-Åke Nygren, Sandrine Palcy, Andreas Plückthun, Bojan Polic, Michael Przybylski, Petri Saviranta, Alan Sawyer, David J Sherman, Arne Skerra, Markus Templin, Marius Ueffing & Mathias Uhlén doi:10.1038/nmeth0107-13 Abstract | Full text | PDF
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| News and Views | Top |
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4D brain signaling pp19 - 20 Nima Marandi & Arthur Konnerth doi:10.1038/nmeth0107-19 Abstract | Full text | PDF
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See also: Article by Göbel et al. |
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From cryo-EM, multiple protein structures in one shot pp20 - 21 Fred J Sigworth doi:10.1038/nmeth0107-20 Abstract | Full text | PDF
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See also: Brief Communication by Scheres et al. |
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| Brief Communications | Top |
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Targeted chromosome elimination from ES-somatic hybrid cells pp23 - 25 Hiroyuki Matsumura, Masako Tada, Tomomi Otsuji, Kentaro Yasuchika, Norio Nakatsuji, Azim Surani & Takashi Tada Published online: 05 November 2006 | doi:10.1038/nmeth973 Abstract | Full text | PDF
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Disentangling conformational states of macromolecules in 3D-EM through likelihood optimization pp27 - 29 Sjors H W Scheres, Haixiao Gao, Mikel Valle, Gabor T Herman, Paul P B Eggermont, Joachim Frank & Jose-Maria Carazo Published online: 10 December 2006 | doi:10.1038/nmeth992 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Sigworth |
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Tomographic molecular imaging and 3D quantification within adult mouse organs pp31 - 33 Tomas Alanentalo, Amir Asayesh, Harris Morrison, Christina E Lorén, Dan Holmberg, James Sharpe & Ulf Ahlgren Published online: 03 December 2006 | doi:10.1038/nmeth985 Abstract | Full text | PDF
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Sensitive and specific method for detecting G protein–coupled receptor mRNAs pp35 - 37 Arne Hansen, Yidong Chen, Jason M Inman, Quang N Phan, Zhi-Qing Qi, Charlie C Xiang, Miklos Palkovits, Natasha Cherman, Sergei A Kuznetsov, Pamela G Robey, Eva Mezey & Michael J Brownstein Published online: 19 November 2006 | doi:10.1038/nmeth977 Abstract | Full text | PDF
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Fast manipulation of cellular cAMP level by light in vivo pp39 - 42 Saskia Schröder-Lang, Martin Schwärzel, Reinhard Seifert, Timo Strünker, Suneel Kateriya, Jens Looser, Masakatsu Watanabe, U Benjamin Kaupp, Peter Hegemann & Georg Nagel Published online: 26 November 2006 | doi:10.1038/nmeth975 Abstract | Full text | PDF
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An Escherichia coli expression–based method for heme substitution pp43 - 45 Joshua J Woodward, Nathaniel I Martin & Michael A Marletta Published online: 24 December 2006 | doi:10.1038/nmeth984 Abstract | Full text | PDF
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Retrograde neuronal tracing with a deletion-mutant rabies virus pp47 - 49 Ian R Wickersham, Stefan Finke, Karl-Klaus Conzelmann & Edward M Callaway Published online: 10 December 2006 | doi:10.1038/nmeth999 Abstract | Full text | PDF
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SILENCE: a new forward genetic technology pp51 - 53 David J Banks & Kenneth A Bradley Published online: 17 December 2006 | doi:10.1038/nmeth991 Abstract | Full text | PDF
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| Articles | Top |
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Transposon-aided capture (TRACA) of plasmids resident in the human gut mobile metagenome pp55 - 61 Brian V Jones & Julian R Marchesi Published online: 26 November 2006 | doi:10.1038/nmeth964 Abstract | Full text | PDF
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Accurate phylogenetic classification of variable-length DNA fragments pp63 - 72 Alice Carolyn McHardy, Héctor García Martín, Aristotelis Tsirigos, Philip Hugenholtz & Isidore Rigoutsos Published online: 10 December 2006 | doi:10.1038/nmeth976 Abstract | Full text | PDF
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Imaging cellular network dynamics in three dimensions using fast 3D laser scanning pp73 - 79 Werner Göbel, Björn M Kampa & Fritjof Helmchen Published online: 03 December 2006 | doi:10.1038/nmeth989 Abstract | Full text | PDF
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| Supplementary Information See also: News and Views by Marandi & Konnerth |
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Major signal increase in fluorescence microscopy through dark-state relaxation pp81 - 86 Gerald Donnert, Christian Eggeling & Stefan W Hell Published online: 10 December 2006 | doi:10.1038/nmeth986 Abstract | Full text | PDF
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SCALEs: multiscale analysis of library enrichment pp87 - 93 Michael D Lynch, Tanya Warnecke & Ryan T Gill Published online: 12 November 2006 | doi:10.1038/nmeth946 Abstract | Full text | PDF
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| Technology Feature | Top |
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The shape of things pp95 - 102 Michael Eisenstein doi:10.1038/nmeth0107-95 Abstract | Full text | PDF
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| Corrigendum | Top |
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Corrigendum: QUICKstep and GS-TAP: new moves for protein-interaction analysis p103 Pascal Braun, Michael E Cusick & Marc Vidal doi:10.1038/nmeth0107-103 Full text | PDF
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| Application Notes | Top |
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Solving the multiplexing–dynamic range conundrum with Diffractive Optics Technology (dot™) Jean-Francois Houle & Sriram Kumaraswamy
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Automated sorting of genetically engineered embryonic stem cells for generation of mouse models Gunther Kauselmann, Heidrun Kern, Anne Klein-Vehne, Torsten Müller, Annette Pfennig & Branko Zevnik
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Toponome Imaging System (TIS): imaging the proteome with functional resolution Marcus Bode & Andreas Krusche
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