ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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December 10 2008 |
December 3 2008 |
November 26 2008 |
November 19 2008 |
November 12 2008 |
November 5 2008 |
October 29 2008 |
October 22 2008 |
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September 24 2008 |
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September 10 2008 |
September 3 2008 |
August 27 2008 |
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March 19 2008 |
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February 6 2008 |
January 30 2008
December 17 2008
Commentary
Accruing Preclinical Evidence about Metabotropic Glutamate 5 Receptor Antagonists as Treatments for Drug Dependence Highlights the Irreplaceable Contributions of Animal Studies to the Discovery of New Medications for Human Disorders
Athina Markou
Neuropsychopharmacology advance online publication, December 17, 2008; doi:10.1038/npp.2008.218
Original Articles
Neuroelectric Signatures of Reward Learning and Decision-Making in the Human Nucleus Accumbens
Michael X Cohen, Nikolai Axmacher, Doris Lenartz, Christian E Elger, Volker Sturm and Thomas E Schlaepfer
Neuropsychopharmacology advance online publication, December 17, 2008; doi:10.1038/npp.2008.222
Nicotine Exposure During Adolescence Induces a Depression-Like State in Adulthood
Sergio D Iñiguez, Brandon L Warren, Eric M Parise, Lyonna F Alcantara, Brittney Schuh, Melissa L Maffeo, Zarko Manojlovic and Carlos A Bolaños-Guzmán
Neuropsychopharmacology advance online publication, December 17, 2008; doi:10.1038/npp.2008.220
Involvement of Inferior Parietal Lobules in Prospective Memory Impairment during Acute MDMA (Ecstasy) Intoxication: An Event-Related fMRI Study
Johannes G Ramaekers, Kim P C Kuypers, Marleen Wingen, Armin Heinecke and Elia Formisano
Neuropsychopharmacology advance online publication, December 17, 2008; doi:10.1038/npp.2008.219
December 10 2008
Original Articles
Assessment of Glutamate Transporter GLAST (EAAT1)-Deficient Mice for Phenotypes Relevant to the Negative and Executive/Cognitive Symptoms of Schizophrenia
Rose-Marie Karlsson, Kohichi Tanaka, Lisa M Saksida, Timothy J Bussey, Markus Heilig and Andrew Holmes
Neuropsychopharmacology advance online publication, December 10, 2008; doi:10.1038/npp.2008.215
TRH-Receptor-Type-2-Deficient Mice are Euthyroid and Exhibit Increased Depression and Reduced Anxiety Phenotypes
Yuhua Sun, Bojana Zupan, Bruce M Raaka, Miklos Toth and Marvin C Gershengorn
Neuropsychopharmacology advance online publication, December 10, 2008; doi:10.1038/npp.2008.217
Differential Effects of the CRF-R1 Antagonist GSK876008 on Fear-Potentiated, Light- and CRF-Enhanced Startle Suggest Preferential Involvement in Sustained vs Phasic Threat Responses
David Walker, Yong Yang, Emiliangelo Ratti, Mauro Corsi, David Trist and Michael Davis
Neuropsychopharmacology advance online publication, December 10, 2008; doi:10.1038/npp.2008.210
December 3 2008
Original Articles
Divalproex ER Combined with Olanzapine or Risperidone for Treatment of Acute Exacerbations of Schizophrenia
Daniel E Casey, David G Daniel, Carol Tamminga, John M Kane, Tram Tran-Johnson, Patricia Wozniak, Walid Abi-Saab, Jeff Baker, Laura Redden, Nicholas Greco and Mario Saltarelli
Neuropsychopharmacology advance online publication, December 3, 2008; doi:10.1038/npp.2008.209
White Matter Alterations in Deficit Schizophrenia
Laura M Rowland, Elena A Spieker, Alan Francis, Peter B Barker, William T Carpenter and Robert W Buchanan
Neuropsychopharmacology advance online publication, December 3, 2008; doi:10.1038/npp.2008.207
Antiamnesic and Neuroprotective Effects of the Aminotetrahydrofuran Derivative ANAVEX1-41 Against Amyloid 
25–35-Induced Toxicity in Mice
Vanessa Villard, Julie Espallergues, Emeline Keller, Tursun Alkam, Atsumi Nitta, Kiyofumi Yamada, Toshitaka Nabeshima, Alexandre Vamvakides and Tangui Maurice
Neuropsychopharmacology advance online publication, December 3, 2008; doi:10.1038/npp.2008.212
Patients with Schizophrenia have a Reduced Neural Response to Both Unpredictable and Predictable Primary Reinforcers
James A Waltz, Julie B Schweitzer, James M Gold, Pradeep K Kurup, Thomas J Ross, Betty Jo Salmeron, Emma Jane Rose, Samuel M McClure and Elliot A Stein
Neuropsychopharmacology advance online publication, December 3, 2008; doi:10.1038/npp.2008.214
Interaction Between Two Independent CNR1 Variants Increases Risk for Cocaine Dependence in European Americans: A Replication Study in Family-Based Sample and Population-Based Sample
Lingjun Zuo, Henry R Kranzler, Xingguang Luo, Bao-zhu Yang, Roger Weiss, Kathleen Brady, James Poling, Lindsay Farrer and Joel Gelernter
Neuropsychopharmacology advance online publication, December 3, 2008; doi:10.1038/npp.2008.206
November 26 2008
Original Articles
Suppression of 
-Oscillations in the Dorsolateral Prefrontal Cortex following Long Interval Cortical Inhibition: A TMS–EEG Study
Faranak Farzan, Mera S Barr, Willy Wong, Robert Chen, Paul B Fitzgerald and Zafiris J Daskalakis
Neuropsychopharmacology advance online publication, November 26, 2008; doi:10.1038/npp.2008.211
Role of Variation in the Serotonin Transporter Protein Gene (SLC6A4) in Trait Disturbances in the Ventral Anterior Cingulate in Bipolar Disorder
Maulik P Shah, Fei Wang, Jessica H Kalmar, Lara G Chepenik, Karen Tie, Brian Pittman, Monique M Jones, R Todd Constable, Joel Gelernter and Hilary P Blumberg
Neuropsychopharmacology advance online publication, November 26, 2008; doi:10.1038/npp.2008.204
November 19 2008
Original Articles
Acute Stress Responsiveness of the Neurotrophin BDNF in the Rat Hippocampus is Modulated by Chronic Treatment with the Antidepressant Duloxetine
Raffaella Molteni, Francesca Calabrese, Annamaria Cattaneo, Michele Mancini, Massimo Gennarelli, Giorgio Racagni and Marco A Riva
Neuropsychopharmacology advance online publication, November 19, 2008; doi:10.1038/npp.2008.208
CRF1 and CRF2 Receptors are Required for Potentiated Startle to Contextual but not Discrete Cues
Victoria B Risbrough, Mark A Geyer, Richard L Hauger, Sarah Coste, Mary Stenzel-Poore, Wolfgang Wurst and Florian Holsboer
Neuropsychopharmacology advance online publication, November 19, 2008; doi:10.1038/npp.2008.205
November 12 2008
Original Articles
Glucocorticoids and Lithium Reciprocally Regulate the Proliferation of Adult Dentate Gyrus-Derived Neural Precursor Cells Through GSK-3 and -Catenin/TCF Pathway
Shuken Boku, Shin Nakagawa, Takahiro Masuda, Hiroyuki Nishikawa, Akiko Kato, Yuji Kitaichi, Takeshi Inoue and Tsukasa Koyama
Neuropsychopharmacology advance online publication, November 12, 2008; doi:10.1038/npp.2008.198
Cocaine- and Amphetamine-Regulated Transcript Peptide Plays a Role in the Manifestation of Depression: Social Isolation and Olfactory Bulbectomy Models Reveal Unifying Principles
Manoj P Dandekar, Praful S Singru, Dadasaheb M Kokare and Nishikant K Subhedar
Neuropsychopharmacology advance online publication, November 12, 2008; doi:10.1038/npp.2008.201
Serotonin Depletion Impairs Waiting but not Stop-Signal Reaction Time in Rats: Implications for Theories of the Role of 5-HT in Behavioral Inhibition
Dawn M Eagle, Olivia Lehmann, David EH Theobald, Yolanda Pena, Rasheed Zakaria, Rhia Ghosh, Jeffrey W Dalley and Trevor W Robbins
Neuropsychopharmacology advance online publication, November 12, 2008; doi:10.1038/npp.2008.202
A Randomized, Placebo-Controlled Study of Memantine as Adjunctive Treatment in Patients with Schizophrenia
Jeffrey A Lieberman, Kelly Papadakis, John Csernansky, Robert Litman, Jan Volavka, Xinwei Daniel Jia and Allyson Gage for the MEM-MD-29 Study Group
Neuropsychopharmacology advance online publication, November 12, 2008; doi:10.1038/npp.2008.200
November 5 2008
Original Articles
The Dopamine D2 Receptors in High-Affinity State and D3 Receptors in Schizophrenia: A Clinical [11C]-(+)-PHNO PET Study
Ariel Graff-Guerrero, Romina Mizrahi, Ofer Agid, Heidi Marcon, Penny Barsoum, Pablo Rusjan, Alan A Wilson, Robert Zipursky and Shitij Kapur
Neuropsychopharmacology advance online publication, November 5, 2008; doi:10.1038/npp.2008.199
Detection of Genetic Association and a Functional Polymorphism of Dynamin 1 Gene with Nicotine Dependence in European and African Americans
Qing Xu, Weihua Huang, Thomas J Payne, Jennie Z Ma and Ming D Li
Neuropsychopharmacology advance online publication, November 5, 2008; doi:10.1038/npp.2008.197
October 29 2008
Original Article
Behavioral Economic Assessment of Price and Cocaine Consumption Following Self-Administration Histories that Produce Escalation of Either Final Ratios or Intake
Erik B Oleson and David CS Roberts
Neuropsychopharmacology advance online publication, October 29, 2008; doi:10.1038/npp.2008.195
October 22 2008
Original Articles
Dopamine Type-1 Receptor Binding in Major Depressive Disorder Assessed Using Positron Emission Tomography and [11C]NNC-112
Dara M Cannon, Jacqueline M Klaver, Summer A Peck, Denise Rallis-Voak, Kristine Erickson and Wayne C Drevets
Neuropsychopharmacology advance online publication, October 22, 2008; doi:10.1038/npp.2008.194
The 
-Receptor Antagonist BD-1063 Decreases Ethanol Intake and Reinforcement in Animal Models of Excessive Drinking
Valentina Sabino, Pietro Cottone, Yu Zhao, Malliga R Iyer, Luca Steardo Jr, Luca Steardo, Kenner C Rice, Bruno Conti, George F Koob and Eric P Zorrilla
Neuropsychopharmacology advance online publication, October 22, 2008; doi:10.1038/npp.2008.192
Novelty Determines the Effects of Olfactory Enrichment on Memory and Neurogenesis Through Noradrenergic Mechanisms
Alexandra Veyrac, Joëlle Sacquet, Véronique Nguyen, Marc Marien, François Jourdan and Anne Didier
Neuropsychopharmacology advance online publication, October 22, 2008; doi:10.1038/npp.2008.191
October 15 2008
Original Articles
The CRF System Mediates Increased Passive Stress-Coping Behavior Following the Loss of a Bonded Partner in a Monogamous Rodent FREE
Oliver J Bosch, Hemanth P Nair, Todd H Ahern, Inga D Neumann and Larry J Young
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.154
Requirement of AQP4 for Antidepressive Efficiency of Fluoxetine: Implication in Adult Hippocampal Neurogenesis
Hui Kong, Luo-lin Sha, Yi Fan, Ming Xiao, Jian-hua Ding, Jie Wu and Gang Hu
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.185
Dopamine Uptake Changes Associated with Cocaine Self-Administration
Erik B Oleson, Sanjay Talluri, Steven R Childers, James E Smith, David C S Roberts, Keith D Bonin and Evgeny A Budygin
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.186
-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate
Matthew D Wiley, Laura B Poveromo, John Antapasis, Carolina M Herrera and Carlos A Bolaños Guzmán
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.188
A Functional Haplotype Implicated in Vulnerability to Develop Cocaine Dependence is Associated with Reduced PDYN Expression in Human Brain
Vadim Yuferov, Fei Ji, David A Nielsen, Orna Levran, Ann Ho, Susan Morgello, Ruijin Shi, Jurg Ott and Mary Jeanne Kreek
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.187
Postsynaptic 
-2 Adrenergic Receptors are Critical for the Antidepressant-Like Effects of Desipramine on Behavior
Han-Ting Zhang, Lisa R Whisler, Ying Huang, Yang Xiang and James M O'Donnell
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.184
Association of Changes in Norepinephrine and Serotonin Transporter Expression with the Long-Term Behavioral Effects of Antidepressant Drugs
Zaorui Zhao, Han-Ting Zhang, Elianna Bootzin, Mark J Millan and James M O'Donnell
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.183
Letter to the Editor
On the Use of Protein Turnover and Half-Lives
Michael J Kuhar
Neuropsychopharmacology advance online publication, October 15, 2008; doi:10.1038/npp.2008.190
October 8 2008
Original Articles
Effects of Topiramate and Other Anti-Glutamatergic Drugs on the Acute Intoxicating Actions of Ethanol in Mice: Modulation by Genetic Strain and Stress
Yi-Chyan Chen and Andrew Holmes
Neuropsychopharmacology advance online publication, October 8, 2008; doi:10.1038/npp.2008.182
Programmed Acute Electrical Stimulation of Ventral Tegmental Area Alleviates Depressive-Like Behavior
Alexander Friedman, Michael Frankel, Yakov Flaumenhaft, Avia Merenlender, Albert Pinhasov, Yuval Feder, Michal Taler, Irit Gil-Ad, Moshe Abeles and Gal Yadid
Neuropsychopharmacology advance online publication, October 8, 2008; doi:10.1038/npp.2008.177
Suppression of the MEK/ERK Signaling Pathway Reverses Depression-like Behaviors of CRF2-Deficient Mice
Cedomir Todorovic, Tessi Sherrin, Matthew Pitts, Cathrin Hippel, Martin Rayner and Joachim Spiess
Neuropsychopharmacology advance online publication, October 8, 2008; doi:10.1038/npp.2008.178
-Tocopherol Protects Against Oxidative Stress in the Fragile X Knockout Mouse: an Experimental Therapeutic Approach for the Fmr1 Deficiency
Yolanda de Diego-Otero, Yanina Romero-Zerbo, Rajaa el Bekay, Juan Decara, Lourdes Sanchez, Fernando Rodriguez-de Fonseca and Ignacio del Arco-Herrera
Neuropsychopharmacology advance online publication, October 8, 2008; doi:10.1038/npp.2008.152
October 1 2008
Original Articles
Neurokinin1 Antagonists Potentiate Antidepressant Properties of Serotonin Reuptake Inhibitors, Yet Blunt Their Anxiogenic Actions: A Neurochemical, Electrophysiological, and Behavioral Characterization
Alain Gobert, Mauricette Brocco, Anne Dekeyne, Benjamin Di Cara, Gaëlle Bouchez, Françoise Lejeune, Robert L Gannon and Mark J Millan
Neuropsychopharmacology advance online publication, October 1, 2008; doi:10.1038/npp.2008.176
Involvement of Amygdala Dopamine and Nucleus Accumbens NMDA Receptors in Ethanol-Seeking Behavior in Mice
Christina M Gremel and Christopher L Cunningham
Neuropsychopharmacology advance online publication, October 1, 2008; doi:10.1038/npp.2008.179
Evidence Why Paroxetine Dose Escalation is Not Effective in Major Depressive Disorder: A Randomized Controlled Trial With Assessment of Serotonin Transporter Occupancy
Henricus G Ruhé, Jan Booij, Henk C v Weert, Johannes B Reitsma, Eric J F Fransen, Martin C Michel and Aart H Schene
Neuropsychopharmacology advance online publication, October 1, 2008; doi:10.1038/npp.2008.148
Response Perseveration and Ventral Prefrontal Sensitivity to Reward and Punishment in Male Problem Gamblers and Smokers
Michiel B de Ruiter, Dick J Veltman, Anna E Goudriaan, Jaap Oosterlaan, Zsuzsika Sjoerds and Wim van den Brink
Neuropsychopharmacology advance online publication, October 1, 2008; doi:10.1038/npp.2008.175
September 24 2008
Original Article
GABRG1 and GABRA2 as Independent Predictors for Alcoholism in Two Populations
Mary-Anne Enoch, Colin A Hodgkinson, Qiaoping Yuan, Bernard Albaugh, Matti Virkkunen and David Goldman
Neuropsychopharmacology advance online publication, September 24, 2008; doi:10.1038/npp.2008.171
September 17 2008
Original Articles
Dopamine D2 and Adenosine A2A Receptors Regulate NMDA-Mediated Excitation in Accumbens Neurons Through A2A–D2 Receptor Heteromerization
Karima Azdad, David Gall, Amina S Woods, Catherine Ledent, Sergi Ferré and Serge N Schiffmann
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.144
mGluR5 Antagonism Attenuates Methamphetamine Reinforcement and Prevents Reinstatement of Methamphetamine-Seeking Behavior in Rats
Justin T Gass, Megan P H Osborne, Noreen L Watson, Jordan L Brown and M Foster Olive
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.140
Two-Week Treatment With the Selective Serotonin Reuptake Inhibitor Citalopram Reduces Contextual Anxiety but Not Cued Fear in Healthy Volunteers: A Fear-Potentiated Startle Study
Christian Grillon, Chanen Chavis, Matthew F Covington and Daniel S Pine
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.141
Desipramine Modulation of -, -Synuclein, and the Norepinephrine Transporter in an Animal Model of Depression
Alexis M Jeannotte, John G McCarthy, Eva E Redei and Anita Sidhu
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.146
Antidepressants Influence Somatostatin Levels and Receptor Pharmacology in Brain
Eleftherios Pallis, Anna Vasilaki, Dominique Fehlmann, Andreas Kastellakis, Daniel Hoyer, Christina Spyraki and Kyriaki Thermos
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.133
Prodynorphin-Derived Peptides Are Critical Modulators of Anxiety and Regulate Neurochemistry and Corticosterone
Walter Wittmann, Eduard Schunk, Iris Rosskothen, Stefano Gaburro, Nicolas Singewald, Herbert Herzog and Christoph Schwarzer
Neuropsychopharmacology advance online publication, September 17, 2008; doi:10.1038/npp.2008.142
September 10 2008
Original Articles
Ethanol Enhances Glutamate Transmission by Retrograde Dopamine Signaling in a Postsynaptic Neuron/Synaptic Bouton Preparation From the Ventral Tegmental Area
Chunyu Deng, Ke-Yong Li, Chunyi Zhou and Jiang-Hong Ye
Neuropsychopharmacology advance online publication, September 10, 2008; doi:10.1038/npp.2008.143
Glucocorticoid Receptor Blockade Normalizes Hippocampal Alterations and Cognitive Impairment in Streptozotocin-Induced Type 1 Diabetes Mice
Yanina Revsin, Niels V Rekers, Mieke C Louwe, Flavia E Saravia, Alejandro F De Nicola, E Ron de Kloet and Melly S Oitzl
Neuropsychopharmacology advance online publication, September 10, 2008; doi:10.1038/npp.2008.136
Behavioral and Neurochemical Changes Induced by Oxycodone Differ Between Adolescent and Adult Mice FREE
Yong Zhang, Roberto Picetti, Eduardo R Butelman, Stefan D Schlussman, Ann Ho and Mary Jeanne Kreek
Neuropsychopharmacology advance online publication, September 10, 2008; doi:10.1038/npp.2008.134
September 3 2008
Original Articles
Abstinence from Chronic Cocaine Self-Administration Alters Striatal Dopamine Systems in Rhesus Monkeys
Thomas J R Beveridge, Hilary R Smith, Michael A Nader and Linda J Porrino
Neuropsychopharmacology advance online publication, September 3, 2008; doi:10.1038/npp.2008.135
Proline Affects Brain Function in 22q11DS Children with the Low Activity COMT158 Allele
Jacob A S Vorstman, Bruce I Turetsky, Monique E J Sijmens-Morcus, Monique G de Sain, Bert Dorland, Mirjam Sprong, Eric F Rappaport, Frits A Beemer, Beverly S Emanuel, René S Kahn, Herman van Engeland and Chantal Kemner
Neuropsychopharmacology advance online publication, September 3, 2008; doi:10.1038/npp.2008.132
August 27 2008
Original Articles
9-Tetrahydrocannabinol Induces Dopamine Release in the Human Striatum
Matthijs G Bossong, Bart NM van Berckel, Ronald Boellaard, Lineke Zuurman, Robert C Schuit, Albert D Windhorst, Joop M A van Gerven, Nick F Ramsey, Adriaan A Lammertsma and René S Kahn
Neuropsychopharmacology advance online publication, August 27, 2008; doi:10.1038/npp.2008.138
Olfactory Receptor Neuron Dysfunction in Schizophrenia
Bruce I Turetsky, Chang-Gyu Hahn, Steven E Arnold and Paul J Moberg
Neuropsychopharmacology advance online publication, August 27, 2008; doi:10.1038/npp.2008.139
August 20 2008
Original Articles
A History of Corticosterone Exposure Regulates Fear Extinction and Cortical NR2B, GluR2/3, and BDNF
Shannon L Gourley, Alexia T Kedves, Peter Olausson and Jane R Taylor
Neuropsychopharmacology advance online publication, August 20, 2008; doi:10.1038/npp.2008.123
A Data Mining Approach to In Vivo Classification of Psychopharmacological Drugs
Neri Kafkafi, Daniel Yekutieli and Greg I Elmer
Neuropsychopharmacology advance online publication, August 20, 2008; doi:10.1038/npp.2008.103
August 13 2008
Original Articles
Loss of Cocaine Locomotor Response in Pitx3-Deficient Mice Lacking a Nigrostriatal Pathway
Jeff A Beeler, Zhen Fang Huang Cao, Mazen A Kheirbek and Xiaoxi Zhuang
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.117
Augmentation of Morphine-Induced Sensitization but Reduction in Morphine Tolerance and Reward in Delta-Opioid Receptor Knockout Mice
V I Chefer and T S Shippenberg
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.128
Effects of the Brain-Derived Neurotrophic Growth Factor Val66Met Variation on Hippocampus Morphology in Bipolar Disorder
Lara G Chepenik, Carolyn Fredericks, Xenophon Papademetris, Linda Spencer, Cheryl Lacadie, Fei Wang, Brian Pittman, James S Duncan, Lawrence H Staib, Ronald S Duman, Joel Gelernter and Hilary P Blumberg
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.107
Metabotropic Glutamate Receptors 5 Blockade Reverses Spatial Memory Deficits in a Mouse Model of Parkinson's Disease
Elvira De Leonibus, Francesca Managò, Francesco Giordani, Francesco Petrosino, Sebastien Lopez, Alberto Oliverio, Marianne Amalric and Andrea Mele
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.129
DAT Genotype Modulates Brain and Behavioral Responses Elicited by Cigarette Cues
Teresa R Franklin, Falk W Lohoff, Ze Wang, Nathan Sciortino, Derek Harper, Yin Li, Will Jens, Jeffrey Cruz, Kyle Kampman, Ron Ehrman, Wade Berrettini, John A Detre, Charles P O'Brien and Anna Rose Childress
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.124
Genetic Association of the CHRNA6 and CHRNB3 Genes with Tobacco Dependence in a Nationally Representative Sample
Nicole R Hoft, Robin P Corley, Matthew B McQueen, Isabel R Schlaepfer, David Huizinga and Marissa A Ehringer
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.122
Mechanisms of Withdrawal-Associated Increases in Heroin Self-Administration: Pharmacologic Modulation of Heroin vs Food Choice in Heroin-Dependent Rhesus Monkeys
S Stevens Negus and Kenner C Rice
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.127
In Vivo Evidence for Alcohol-Induced Neurochemical Changes in Rat Brain Without Protracted Withdrawal, Pronounced Thiamine Deficiency, or Severe Liver Damage
Natalie M Zahr, Dirk Mayer, Shara Vinco, Juan Orduna, Richard Luong, Edith V Sullivan and Adolf Pfefferbaum
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.119
Evidence for Selective microRNAs and their Effectors as Common Long-Term Targets for the Actions of Mood Stabilizers
Rulun Zhou, Peixiong Yuan, Yun Wang, Joshua G Hunsberger, Abdel Elkahloun, Yanling Wei, Patricia Damschroder-Williams, Jing Du, Guang Chen and Husseini K Manji
Neuropsychopharmacology advance online publication, August 13, 2008; doi:10.1038/npp.2008.131
August 6 2008
Original Articles
Sustained Administration of Pramipexole Modifies the Spontaneous Firing of Dopamine, Norepinephrine, and Serotonin Neurons in the Rat Brain
O Chernoloz, M El Mansari and P Blier
Neuropsychopharmacology advance online publication, August 6, 2008; doi:10.1038/npp.2008.114
Smoked Medicinal Cannabis for Neuropathic Pain in HIV: A Randomized, Crossover Clinical Trial
Ronald J Ellis, Will Toperoff, Florin Vaida, Geoffrey van den Brande, James Gonzales, Ben Gouaux, Heather Bentley and J Hampton Atkinson
Neuropsychopharmacology advance online publication, August 6, 2008; doi:10.1038/npp.2008.120
D2-Receptor Upregulation is Dependent upon Temporal Course of D2-Occupancy: A Longitudinal [11C]-Raclopride PET Study in Cats
Nathalie Ginovart, Alan A Wilson, Doug Hussey, Sylvain Houle and Shitij Kapur
Neuropsychopharmacology advance online publication, August 6, 2008; doi:10.1038/npp.2008.116
July 30 2008
Original Articles
ErbB4 Genotype Predicts Left Frontotemporal Structural Connectivity in Human Brain
Andreas Konrad, Goran Vucurevic, Francesco Musso, Peter Stoeter, Norbert Dahmen and Georg Winterer
Neuropsychopharmacology advance online publication, July 30, 2008; doi:10.1038/npp.2008.112
The Ventral Pallidum is Critically Involved in the Development and Expression of Morphine-Induced Sensitization
Amanda L Mickiewicz, Jeanine E Dallimore and T Celeste Napier
Neuropsychopharmacology advance online publication, July 30, 2008; doi:10.1038/npp.2008.111
Brain Drug-Metabolizing Cytochrome P450 Enzymes are Active In Vivo, Demonstrated by Mechanism-Based Enzyme Inhibition
Sharon Miksys and Rachel F Tyndale
Neuropsychopharmacology advance online publication, July 30, 2008; doi:10.1038/npp.2008.110
Dopaminergic Modulation of Risk-Based Decision Making
Jennifer R St Onge and Stan B Floresco
Neuropsychopharmacology advance online publication, July 30, 2008; doi:10.1038/npp.2008.121
July 23 2008
Original Article
Increased OPRM1 DNA Methylation in Lymphocytes of Methadone-Maintained Former Heroin Addicts
David A Nielsen, Vadim Yuferov, Sara Hamon, Colin Jackson, Ann Ho, Jurg Ott and Mary Jeanne Kreek
Neuropsychopharmacology advance online publication, July 23, 2008; doi:10.1038/npp.2008.108
July 9 2008
Original Articles
Diffusion Tensor Tractography in Mesencephalic Bundles: Relation to Mental Flexibility in Detoxified Alcohol-Dependent Subjects
Sandra Chanraud, Michel Reynaud, Michèle Wessa, Jani Penttilä, Nikoleta Kostogianni, Arnaud Cachia, Eric Artiges, Françoise Delain, Murielle Perrin, Henri-Jean Aubin, Yann Cointepas, Catherine Martelli and Jean-Luc Martinot
Neuropsychopharmacology advance online publication, July 9, 2008; doi:10.1038/npp.2008.101
Tiagabine Increases [11C]flumazenil Binding in Cortical Brain Regions in Healthy Control Subjects
W Gordon Frankle, Raymond Y Cho, Rajesh Narendran, N Scott Mason, Shivangi Vora, Maralee Litschge, Julie C Price, David A Lewis and Chester A Mathis
Neuropsychopharmacology advance online publication, July 9, 2008; doi:10.1038/npp.2008.104
Early Parental Deprivation in the Marmoset Monkey Produces Long-Term Changes in Hippocampal Expression of Genes Involved in Synaptic Plasticity and Implicated in Mood Disorder
Amanda J Law, Qi Pei, Mary Walker, Helen Gordon-Andrews, Cyndi Shannon Weickert, Joram Feldon, Christopher R Pryce and Paul J Harrison
Neuropsychopharmacology advance online publication, July 9, 2008; doi:10.1038/npp.2008.106
July 2 2008
Original Articles
Short Onset of Action of a Serotonin Reuptake Inhibitor When Used to Reduce Premenstrual Irritability
Mikael Landén, Helena Erlandsson, Finn Bengtsson, Björn Andersch and Elias Eriksson
Neuropsychopharmacology advance online publication, July 2, 2008; doi:10.1038/npp.2008.86
Evidence for
1-Adrenergic Receptor Involvement in Amygdalar Corticotropin-Releasing Factor Gene Expression: Implications for Cocaine Withdrawal
Carla A Rudoy, Arith-Ruth S Reyes and Elisabeth J Van Bockstaele
Neuropsychopharmacology advance online publication, July 2, 2008; doi:10.1038/npp.2008.102
June 25 2008
Corrigendum
Pharmacologically Induced Hypogonadism and Sexual Function in Healthy Young Women and Men FREE
Peter J Schmidt, Emma M Steinberg, Paula Palladino Negro, Nazli Haq, Carolyn Gibson and David R Rubinow
Neuropsychopharmacology advance online publication, June 25, 2008; doi:10.1038/npp.2008.91
Original Articles
Effect of Cocaine on Fas-Associated Protein with Death Domain in the Rat Brain: Individual Differences in a Model of Differential Vulnerability to Drug Abuse
María-Julia García-Fuster, Sarah M Clinton, Stanley J Watson and Huda Akil
Neuropsychopharmacology advance online publication, June 25, 2008; doi:10.1038/npp.2008.88
Anxiolytic Effects in Mice of a Dual Blocker of Fatty Acid Amide Hydrolase and Transient Receptor Potential Vanilloid Type-1 Channels
Vincenzo Micale, Luigia Cristino, Alessandra Tamburella, Stefania Petrosino, Gian Marco Leggio, Filippo Drago and Vincenzo Di Marzo
Neuropsychopharmacology advance online publication, June 25, 2008; doi:10.1038/npp.2008.98
June 18 2008
Original Articles
Enhanced Negative Emotion and Alcohol Craving, and Altered Physiological Responses Following Stress and Cue Exposure in Alcohol Dependent Individuals
Rajita Sinha, Helen C Fox, Kwangik A Hong, Keri Bergquist, Zubin Bhagwagar and Kristen M Siedlarz
Neuropsychopharmacology advance online publication, June 18, 2008; doi:10.1038/npp.2008.78
Abstinence following Alcohol Drinking Produces Depression-Like Behavior and Reduced Hippocampal Neurogenesis in Mice
Jennie R Stevenson, Jason P Schroeder, Kimberly Nixon, Joyce Besheer, Fulton T Crews and Clyde W Hodge
Neuropsychopharmacology advance online publication, June 18, 2008; doi:10.1038/npp.2008.90
June 4 2008
Original Articles
A Differential Role for the Adenosine A2A Receptor in Opiate Reinforcement vs Opiate-Seeking Behavior
Robyn Mary Brown, Jennifer Lynn Short, Michael Scott Cowen, Catherine Ledent and Andrew John Lawrence
Neuropsychopharmacology advance online publication, June 4, 2008; doi:10.1038/npp.2008.72
Narp Deletion Blocks Extinction of Morphine Place Preference Conditioning
Hans S Crombag, Mercy Dickson, Megan Dinenna, Alexander W Johnson, Mark S Perin, Peter C Holland, Jay M Baraban and Irving M Reti
Neuropsychopharmacology advance online publication, June 4, 2008; doi:10.1038/npp.2008.80
Altered Negative BOLD Responses in the Default-Mode Network during Emotion Processing in Depressed Subjects
Simone Grimm, Peter Boesiger, Johannes Beck, Daniel Schuepbach, Felix Bermpohl, Martin Walter, Jutta Ernst, Daniel Hell, Heinz Boeker and Georg Northoff
Neuropsychopharmacology advance online publication, June 4, 2008; doi:10.1038/npp.2008.81
Corticolimbic Transcriptome Changes are State-Dependent and Region-Specific in a Rodent Model of Depression and of Antidepressant Reversal
Alexandre Surget, Yingjie Wang, Samuel Leman, Yadira Ibarguen-Vargas, Nicole Edgar, Guy Griebel, Catherine Belzung and Etienne Sibille
Neuropsychopharmacology advance online publication, June 4, 2008; doi:10.1038/npp.2008.76
May 21 2008
Original Articles
DHEA Lessens Depressive-Like Behavior via GABA-ergic Modulation of the Mesolimbic System
Rotem Genud, Avia Merenlender, Iris Gispan-Herman, Rachel Maayan, Abraham Weizman and Gal Yadid
Neuropsychopharmacology advance online publication, May 21, 2008; doi:10.1038/npp.2008.46
Reduced Stress-Sensitivity or Increased Reward Experience: The Psychological Mechanism of Response to Antidepressant Medication
M C Wichers, D Q C M Barge-Schaapveld, N A Nicolson, F Peeters, M de Vries, R Mengelers and J van Os
Neuropsychopharmacology advance online publication, May 21, 2008; doi:10.1038/npp.2008.66
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