Current Issue

Perspective

Wildlife cancer: a conservation perspective

Denise McAloose & Alisa L. Newton

Cancer in wildlife seems to be more prevalent than previously thought and could have considerable effects on the populations of some species. This Perspective discusses the conservation issues raised by cancer in wildlife.

Current Issue

Review

Chemoprevention of lung carcinogenesis in addicted smokers and ex–smokers

Stephen S. Hecht, Fekadu Kassie & Dorothy K. Hatsukami

Chemoprevention of lung carcinogenesis is one potential approach to control the epidemic of lung cancer caused by cigarette smoking. How should we go about this and is using mixtures of chemopreventive agents a useful path to pursue?

Current Issue

Review

Genetic prognostic and predictive markers in colorectal cancer

Axel Walther, Elaine Johnstone, Charles Swanton, Rachel Midgley, Ian Tomlinson & David Kerr

Cancer prevention is a global priority, but history indicates that the journey towards achieving this goal is fraught with difficulties. What can we learn from the past that is applicable to the reality of successful cancer prevention?

Current Issue

Perspective

Cancer prevention research — then and now

Ann M. Bode & Zigang Dong

Cancer prevention is a global priority, but history indicates that the journey towards achieving this goal is fraught with difficulties. What can we learn from the past that is applicable to the reality of successful cancer prevention?

Current issue

Perspective

Apoptosis and cancer: the genesis of a research field

Thomas G. Cotter

Ever since its discovery, apoptosis has been inextricably linked with cancer. This Timeline article seeks to provide insights into the key discoveries in the field and therapeutic applications based on apoptotic strategies.

Current Issue

Research Highlights

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  Signalling:

  Hedgehog doesn't...

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  Therapeutics:

  Dependent on KRAS

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  Senescence:

  Playing games with epigenetics