Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Genomic imprinting has provided insights into epigenetic principles that apply in many contexts. This Timeline highlights lessons for developmental gene regulation by looking back at the emergence of our understanding of imprinting, particularly in mammals, and commenting on current questions and recent progress.