Fundamental concepts in genetics
Our understanding of heredity and the practice of genetic analysis are underpinned by certain fundamental concepts. Each article in this series examines one of these concepts, explaining how it works, how it has contributed to genetics and why it is of continuing importance today. The articles are designed both as an introduction to the concept and an analysis of the latest developments.
2009
June 2009 Advance online publication
Fitness and its role in evolutionary genetics
H. Allen Orr
doi:10.1038/nrg2603
March 2009 Volume 10 No 3
Effective population size and patterns of molecular evolution and variation
Brian Charlesworth
doi:10.1038/nrg2526
February 2009 Volume 10 No 2
Genetics and the understanding of selection
Laurence D. Hurst
doi:10.1038/nrg2506
2008
November 2008 Volume 9 No 11
Epistasis — the essential role of gene interactions in the structure and evolution of genetic systems
Patrick C. Phillips
doi:10.1038/nrg2452
June 2008 Volume 9 No 6
Linkage disequilibrium — understanding the evolutionary past and mapping the medical future
Montgomery Slatkin
doi:10.1038/nrg2361
April 2008 Volume 9 No 4
Heritability in the genomics era — concepts and misconceptions
Peter M. Visscher, William G. Hill & Naomi R. Wray
doi:10.1038/nrg2322
