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Andrew Pollard describes a 1921 study by George Heist and colleagues that pointed to antibody as a correlate of protection against meningococcal disease.
Alan Sher describes a 2002 paper by Martien Kapsenberg and Pawel Kalinski that provided evidence for the conditioning of DCs by microbial compounds to promote TH1 or TH2 cell responses.
Kiyoshi Takeda describes a 2009 paper by Maslowskiet al. that provides the first evidence of a link between microbiota-derived metabolites and human health.