News & Comment

Discusses recent papers on the topography of the interphase chromatin fibre.

Describes how proteins are often synthesized and degraded at their site of action.

Describes how a minimal oscillatory cyclin–CDK module can drive the cell cycle.

Describes the discovery of the NoCut checkpoint.

Describes the identification and structural characterization of the Sec61 translocase.

Describes insights into the type of DNA interactions that are influenced by SMC5–SMC6.

Three classic papers helped reveal how the Spemann organizer builds the vertebrate body.

Highlights the benefits to be gained by panning the older literature for new ideas and methods.

Considers that ribonucleoproteins might bridge the RNA and protein worlds.

Evolutionary theory with implications for cell biology.