Advance online publication
The latest articles are published online ahead of print (AOP) on a weekly basis. These online versions are definitive and may be cited using the digital object identifier (DOI).
Article Types
Research Highlights
HIV: No place to hide | PDF (214 KB)
Published online: 26 October 2009 | doi:10.1038/nrmicro2263
Host response: Damage repair | PDF (206 KB)
Published online: 26 October 2009 | doi:10.1038/nrmicro2264
Reviews
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
Richard T. Eastman & David A. Fidock
Published online: 02 November 2009 | doi:10.1038/nrmicro2239
The emergence of drug-resistant Plasmodium parasites has made the treatment of malaria difficult in some areas. One of the last drugs to which there is no full resistance is artemisinin. Fidock and Eastman describe artemisinin-based combination therapies that aim to decrease the occurrence of drug resistance and that have raised the possibility of malaria eradication.
Bacterial responses to photo-oxidative stress
Eva C. Ziegelhoffer & Timothy J. Donohue
Published online: 02 November 2009 | doi:10.1038/nrmicro2237
Photo-oxidative stress caused by singlet oxygen, a type of reactive oxygen species that is generated by energy transfer to molecular oxygen, can damage cellular components, leading to cell death. In this Review, Donohue and Ziegelhoffer describe the recent advances made in characterizing the bacterial response mechanisms to photo-oxidative stress.
The spectrum of latent tuberculosis: rethinking the biology and intervention strategies
Clifton E. Barry, 3rd, Helena I. Boshoff, Véronique Dartois, Thomas Dick, Sabine Ehrt, JoAnne Flynn, Dirk Schnappinger, Robert J. Wilkinson & Douglas Young
Published online: 26 October 2009 | doi:10.1038/nrmicro2236
Nearly one-third of the world's population is infected with Mycobacterium tuberculosis. In this Review, Young and colleagues describe the different forms the infection can take, how imaging techniques can help us understand the range of infections and how these findings can be used for drug discovery approaches.
Perspectives
Science and society
Defining infections in international travellers through the GeoSentinel surveillance network
Joseph Torresi & Karin Leder
Published online: 02 November 2009 | doi:10.1038/nrmicro2238
Efforts to monitor the range of infectious diseases that affect international travellers and the factors that determine infection rates will provide an evidence base from which more effective preventative measures can be developed. Torresi and Leder review the main findings of one such effort, the GeoSentinel surveillance network.
About AOP
Until print versions of AOP papers are published, they should be cited in the style "Nature Reviews Microbiology AOP, published online day month year; doi:10.1038/nrmicroXXX". Once the print version (identical to the AOP) is published, it should be cited as follows: "Nature Reviews Microbiology volume number, page range (year); doi:10.1038/nrmicroXXX".
