Harmful BMP's. Bone morphogenetic protein (BMP) signaling make breast cancer patients more prone to bone metastasis. Read about Smad pathways role in cell signal causing greater skeletal deformities.

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Oncogene Reviews

PTEN's dynamic users guide. Mechanizing apoptosis is one of many possible future applications involving PTEN. The genes manipulative abilities help to chart out its true role in tumor suppression and genome stability. Read this special reviews issue that showcases PTEN branching involvement in the physiology, pharmacology and genetics of cancer.

Apoptosis reviews series. Read articles on FLIP, Bcl-2 and caspase-independent cell death in this special two-part reviews issue covering the intrinsic and extrinsic pathways of apoptosis.