TABLE OF CONTENTS

Volume 26, Issue 56 (10 December 2007)

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Guest Editors

Guest Editors

Oncogene 26: 7715-7716; doi:10.1038/sj.onc.1210869

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Introduction

DNA double-strand breaks: their cellular and clinical impact?

P A Jeggo and M Löbrich

Oncogene 26: 7717-7719; doi:10.1038/sj.onc.1210868

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Reviews

BRCA2: a universal recombinase regulator

T Thorslund and S C West

Oncogene 26: 7720-7730; doi:10.1038/sj.onc.1210870

Non-homologous end-joining, a sticky affair

D C van Gent and M van der Burg

Oncogene 26: 7731-7740; doi:10.1038/sj.onc.1210871

Activation and regulation of ATM kinase activity in response to DNA double-strand breaks

J-H Lee and T T Paull

Oncogene 26: 7741-7748; doi:10.1038/sj.onc.1210872

ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks

M F Lavin

Oncogene 26: 7749-7758; doi:10.1038/sj.onc.1210880

Breaking down cell cycle checkpoints and DNA repair during antigen receptor gene assembly

E Callén, M C Nussenzweig and A Nussenzweig

Oncogene 26: 7759-7764; doi:10.1038/sj.onc.1210873

Chromatin structure and DNA double-strand break responses in cancer progression and therapy

J A Downs

Oncogene 26: 7765-7772; doi:10.1038/sj.onc.1210874

DNA damage signalling guards against activated oncogenes and tumour progression

J Bartek, J Bartkova and J Lukas

Oncogene 26: 7773-7779; doi:10.1038/sj.onc.1210881

V(D)J and immunoglobulin class switch recombinations: a paradigm to study the regulation of DNA end-joining

P Soulas-Sprauel, P Rivera-Munoz, L Malivert, G Le Guyader, V Abramowski, P Revy and J-P de Villartay

Oncogene 26: 7780-7791; doi:10.1038/sj.onc.1210875

The clinical manifestation of a defective response to DNA double-strand breaks as exemplified by Nijmegen breakage syndrome

I Demuth and M Digweed

Oncogene 26: 7792-7798; doi:10.1038/sj.onc.1210876

DNA double-strand break repair and development

E R Phillips and P J McKinnon

Oncogene 26: 7799-7808; doi:10.1038/sj.onc.1210877

Glioblastoma multiforme: the role of DSB repair between genotype and phenotype

U Fischer and E Meese

Oncogene 26: 7809-7815; doi:10.1038/sj.onc.1210878

Targeted cancer therapies based on the inhibition of DNA strand break repair

M J O'Connor, N M B Martin and G C M Smith

Oncogene 26: 7816-7824; doi:10.1038/sj.onc.1210879

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