Getting to the stem of chronic myeloid leukaemia - pp341 - 350
Michael Savona & Moshe Talpaz
doi:10.1038/nrc2368
Full Text - Getting to the stem of chronic myeloid leukaemia | PDF (647 KB) - Getting to the stem of chronic myeloid leukaemia
More reprogramming tips
Monya Baker
A gene used to reprogram differentiated cells blocks microRNA processing
Published online: 06 March 2008; doi:10.1038/stemcells.2008.43
OncoMed scores drug deal for $1.4 billion with Glaxo
doi:10.1038/451511e
Full Text - OncoMed scores drug deal for $1.4 billion with Glaxo
Tracking cancer to intestinal stem cells
Monya Baker
Two research teams follow cancer to its source
Published online: 30 December 2008; doi:10.1038/stemcells.2008.162
Cancer stem cells, becoming common
Monya Baker
Tumour cells that can initiate a new tumour are not so rare as previously thought, putting the concept of the 'cancer stem cell' under the spotlight again.
Published online: 03 December 2008; doi:10.1038/stemcells.2008.153
Two of a kind
Simone Alves
Cancer stem cells use an embryonic stem cell-like transcriptional program to induce and maintain tumours
Published online: 11 September 2008; doi:10.1038/stemcells.2008.126
Stem cell meeting 2008: in with the old, in with the new
Monya Baker & Natalie DeWitt
Although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.
Published online: 17 July 2008; doi:10.1038/stemcells.2008.108
Full Text - Stem cell meeting 2008: in with the old, in with the new
MYB function in normal and cancer cells - pp523 - 534
Robert G. Ramsay & Thomas J. Gonda
doi:10.1038/nrc2439
Full Text - MYB function in normal and cancer cells | PDF (1,027 KB) - MYB function in normal and cancer cells | Supplementary information - MYB function in normal and cancer cells
Leukaemia: A provoking end? - p407
Nicola McCarthy
doi:10.1038/nrc2412
Full Text - LeukaemiaA provoking end? | PDF (338 KB) - LeukaemiaA provoking end?
Cancer stem cells – old concepts, new insights - pp947 - 958
L Vermeulen, M R Sprick, K Kemper, G Stassi & J P Medema
Published online: 15 February 2008; doi:10.1038/cdd.2008.20
Full Text - Cancer stem cells – old concepts, new insights | PDF (309 KB) - Cancer stem cells – old concepts, new insights
Cancer and embryonic stem cells share genetic fingerprints
Monya Baker
At least two modules of genes promote stemness
Published online: 17 April 2008; doi:10.1038/stemcells.2008.62
Full Text - Cancer and embryonic stem cells share genetic fingerprints
Skin cancer needs beta-catenin
Monya Baker
Without beta-catenin cancer stem cells no longer support tumours
Published online: 03 April 2008; doi:10.1038/stemcells.2008.57
Radiation therapy: Sensitizing stem cells - pp246 - 247
Patrick Goymer
doi:10.1038/nrc2358
Full Text - Radiation therapySensitizing stem cells | PDF (106 KB) - Radiation therapySensitizing stem cells
Drug makers chase cancer stem cells - pp366 - 367
Charlie Schmidt
doi:10.1038/nbt0408-366c
Full Text - Drug makers chase cancer stem cells | PDF (222 KB) - Drug makers chase cancer stem cells
BRCA1 and stem cells: tumour typecasting - pp377 - 379
Matthew J. Smalley, Jorge S. Reis-Filho & Alan Ashworth
Phenotypic variation between tumour types is likely to reflect the nature of the cell of origin and the genes involved in pathogenesis. Compared with most sporadic breast cancers, those arising in carriers of BRCA1 mutations usually have distinctive pathological characteristics. A new study suggests that a role for BRCA1 in the determination of stem-cell fate may explain this phenomenon.
doi:10.1038/ncb0408-377
Full Text - BRCA1 and stem cells: tumour typecasting | PDF (291 KB) - BRCA1 and stem cells: tumour typecasting
Cancer and stem cells: Beckman conference
Monya Baker
Cancer cells emerge when checkpoints fail
Published online: 13 March 2008; doi:10.1038/stemcells.2008.47
Stuck on youth
Jen Middleton
Some cancer stem cells retain an embryonic pathway
Published online: 24 January 2008; doi:10.1038/stemcells.2008.23
Twins yield leukaemia stem cells
Heidi Ledford
doi:10.1038/news.2008.447
MicroRNA reins in tumor-initiating cells
Sarah Webb
A microRNA that silences two oncogenes is quiet in cancer stem cells
Published online: 03 January 2008; doi:10.1038/stemcells.2007.137
Stem cell self-renewal versus differentiation: Tumor suppressor Mei-P26 and miRNAs control the balance - pp713 - 715
Run Shen & Ting Xie
doi:10.1038/cr.2008.79
Full Text - Stem cell self-renewal versus differentiation: Tumor suppressor Mei-P26 and miRNAs control the balance | PDF (336 KB) - Stem cell self-renewal versus differentiation: Tumor suppressor Mei-P26 and miRNAs control the balance
Stem cells: MicroRNAs promote differentiation - p245
Patrick Goymer
doi:10.1038/nrc2357
Full Text - Stem cellsMicroRNAs promote differentiation | PDF (491 KB) - Stem cellsMicroRNAs promote differentiation
The space race
Simone Alves
Defective stem cells physically compete for space in the niche of the Drosophila ovary
Published online: 24 January 2008; doi:10.1038/stemcells.2008.24
