Reprogramming

Monkey embryonic stem cells cloned

Monya Baker

Attempts in humans already under way

Published online: 21 November 2007; doi:10.1038/stemcells.2007.119

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Primate cells cloned by nuclear transfer

Natalie DeWitt

304 monkey oocytes yield 35 blastocysts, 2 cell lines

Published online: 21 November 2007; doi:10.1038/stemcells.2007.118

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Monkey stem cells cloned - pp891

Monya Baker

Advance could renew enthusiasm for the field

Published online: 20 June 2007; doi:10.1038/447891a

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Can opposition to research spur innovation?

Charis Thompson

Moral debates, rhetoric and stem-cell breakthroughs interact

Published online: 13 December 2007; doi:10.1038/stemcells.2007.128

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Adult cells reprogrammed to pluripotency, without tumors

Monya Baker

Just a trio of introduced genes can send cells back in development

Published online: 06 December 2007; doi:10.1038/stemcells.2007.124

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Stem cells: Primates join the club - pp485 - 486

Ian Wilmut & Jane Taylor

Researchers have achieved the testing goal of generating embryonic stem cells from the cells of an adult primate. The procedure used could provide insights into a variety of diseases, if it can be applied in humans.

Published online: 21 November 2007; doi:10.1038/450485a

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Bone marrow transplant paper revives contentious debate on fertility - pp1003

Kendall Powell

Researcher claims adult females can make new eggs.

Published online: 31 August 2007; doi:10.1038/nm0907-1003

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Stem cells: The magic brew - pp260 - 262

Janet Rossant

Researchers have engineered embryonic stem-like cells from normal mouse skin cells. If this method can be translated to humans, patient-specific stem cells could be made without the use of donated eggs or embryos.

Published online: 18 July 2007; doi:10.1038/448260a

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Reprogramming expert makes a lab in two countries

Monya Baker

Shinya Yamanaka's trans-oceanic commute to discover the secrets of pluripotency

Published online: 05 July 2007; doi:10.1038/stemcells.2007.51

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Mice born from cloned sperm

Michael Hopkin

doi:10.1038/news070702-8

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A conversation with Davor Solter of Max-Planck-Institute of Immunobiology

Monya Baker

Much of the work that had previously convinced scientists that only oocytes, and not zygotes, could be used for cloning came from very careful studies by McGrath and Solter in the 1980s1, 2. A few weeks before Kevin Eggan's paper3 was made public, Nature Reports Stem Cells tracked down Davor Solter to learn his thoughts.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.10

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Fertilized eggs reprogram adult-cell genomes

Monya Baker

Findings that fertilized eggs can be used to clone mice raise an old question: how can a single cell manipulate DNA to support an entire organism's development?

Published online: 07 June 2007; doi:10.1038/stemcells.2007.4

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A conversation with Ian Wilmut, Director of the Centre for Regenerative Medicine, University of Edinburgh

Monya Baker

Dolly the sheep came not from the union of sperm and egg but from the mammary cell of one sheep and the unfertilized egg of another. Her birth, more than 10 years ago showed that nuclei from specialized adult cells can be reprogrammed into all the cells of an organism.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.5

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From skin cell to stem cell

Monya Baker

Mouse skin cells made pluripotent by genetic modification can give rise to all types of tissue.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.6

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Mice cloned using fertilized eggs

Monya Baker

Unfertilized eggs have long been the limiting resource for attempts to make genetically tailored human embryonic stem cells. If a new technique for cloning mice from fertilized eggs works in humans, they might not be necessary.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.7

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A conversation with Shinya Yamanaka, Professor at Kyoto University

Monya Baker

A technique to transform specialized cells could pave the way to create patient-specific "embryonic" stem cells, without requiring eggs or embryos.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.9

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Inside the Paper: Cloning from chromosomes

Natalie DeWitt

Published online: 07 June 2007; doi:10.1038/stemcells.2007.30

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Man or beast? Man and beast!

Ian Wilmut

Scientists should try putting human nuclei into animal eggs. These part-animal cells could produce some of the most powerful tools yet for unravelling human disease. Even if this procedure doesn't lead to embryonic stem cells, the attempt has something to teach us.

Published online: 07 June 2007; doi:10.1038/stemcells.2007.3

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