Reprogramming

Human embryos cloned from adult cells

David Cyranoski

doi:10.1038/news.2007.350

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iPS cells and the politics of promise - pp271 - 272

Herbert Gottweis & Stephen Minger

doi:10.1038/nbt0308-271

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Exogenous aids to reprogramming and self-renewal

Monya Baker

Small molecules replace pluripotency gene and Wnt boosts self-renewal and reprogramming

Published online: 13 November 2008; doi:10.1038/stemcells.2008.149

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Embryonic-like stem cells from a single human hair

Monya Baker

Compared to fibroblasts, keratinocytes generate a hundred times more iPS cells in half the time

Published online: 30 October 2008; doi:10.1038/stemcells.2008.142

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Thomas Graf: Cellular identity and transdifferentiation

Monya Baker

In the quest to switch one cell type to another, how far can tweaking transcription factors go?

Published online: 23 October 2008; doi:10.1038/stemcells.2008.140

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Integration-free iPS cells

Monya Baker

Reprogramming does not require permanent genetic modification

Published online: 16 October 2008; doi:10.1038/stemcells.2008.136

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New routes to pluripotency

Monya Baker

Human testis cells become pluripotent in culture

Published online: 09 October 2008; doi:10.1038/stemcells.2008.132

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Cell 'rebooting' technique sidesteps risks

Erika Check Hayden

Virus reprograms cells without disrupting genome.

Published online: 25 September 2008; doi:10.1038/news.2008.1132

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Nerve cells made from elderly patient's skin cells

Monya Baker

Reprogrammed cells may offer insight into neurodegenerative disease.

Published online: 31 July 2008; doi:10.1038/454675b

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'Reprogramming-ready' mice

Monya Baker

Transgenic mice mice offer a source of genetically identically induced pluripotent stem cells

Published online: 10 July 2008; doi:10.1038/stemcells.2008.106

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Easing out the viruses in induced pluripotency

Monya Baker

Four goes to two

Published online: 03 July 2008; doi:10.1038/stemcells.2008.101

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The latest pluripotency factor is a lone warrior

Monya Baker

Ronin takes a place beside Oct4, Nanog and Sox2

Published online: 03 July 2008; doi:10.1038/stemcells.2008.102

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Small molecules boost reprogramming rates

Monya Baker

Induced pluripotent stem cells edge away from viruses

Published online: 03 July 2008; doi:10.1038/stemcells.2008.99

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Stem cells: Tips for priming potency - pp45 - 46

Joseph F. Costello

Introducing just four specific genes into adult cells causes them to regress to an embryonic stem-cell-like state. At 1%, the efficiency of this process is low, but two tips are at hand on how to make improvements.

Published online: 02 July 2008; doi:10.1038/454045a

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How do you know a reprogrammed cell is reprogrammed?

Monya Baker

Scientists consider minimum standards for induced pluripotent stem cells

Published online: 26 June 2008; doi:10.1038/stemcells.2008.97

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Unlocking reprogramming

David Cyranoski & Monya Baker

New strategies could lead to changes in the quality, quantity of induced pluripotent cells

Published online: 12 June 2008; doi:10.1038/stemcells.2008.93

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Embryonic Stem Cells 2.0

Bruce Goldman

Scientists' enthusiasm grows for induced pluripotent cells

Published online: 01 May 2008; doi:10.1038/stemcells.2008.67

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Reprogramming turns an end into a beginning

Monya Baker

Mature B cells from reprogramming-ready mice become pluripotent

Published online: 24 April 2008; doi:10.1038/stemcells.2008.71

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What comes after iPS?

Thomas P. Zwaka

Though applications of reprogrammed cells will be valuable, the questions they engender will be just as important

Published online: 03 April 2008; doi:10.1038/stemcells.2008.54

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Stem cells: 5 things to know before jumping on the iPS bandwagon

David Cyranoski

doi:10.1038/452406a

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A reprogramming rush - p388

Stem-cell research is in danger of falling foul of haste.

Published online: 26 March 2008; doi:10.1038/452388a

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Stem-cell claim gets cold reception

David Cyranoski & Monya Baker

doi:10.1038/452132a

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More reprogramming tips

Monya Baker

A gene used to reprogram differentiated cells blocks microRNA processing

Published online: 06 March 2008; doi:10.1038/stemcells.2008.43

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Reprogramming kinetics

Monya Baker

Virally introduced genes must be active for several days to induce pluripotency

Published online: 06 March 2008; doi:10.1038/stemcells.2008.44

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More induced pluripotency

Monya Baker

Yamanaka's quartet reprograms human skin cells in another lab

Published online: 28 February 2008; doi:10.1038/stemcells.2008.39

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Stomach and liver cells reprogrammed

Monya Baker

Cells need fewer extra gene copies to become pluripotent, and the resulting mice don't get tumours

Published online: 28 February 2008; doi:10.1038/stemcells.2008.40

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Reprogramming kinetics

Monya Baker

Virally introduced genes must be active for more than a week to induce pluripotency

Published online: 14 February 2008; doi:10.1038/stemcells.2008.36

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Stem cells: a national project

David Cyranoski

doi:10.1038/451229a

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Personalizing pluripotency

Monya Baker

A simple skin biopsy can yield stem cells specific to an individual patient

Published online: 10 January 2008; doi:10.1038/stemcells.2007.150

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Stem cells: A new year and a new era - pp135 - 136

Martin F. Pera

Manipulating cells from adult human tissue, scientists have generated cells with the same developmental potential as embryonic stem cells. The research opportunities these exciting observations offer are limitless.

Published online: 09 January 2008; doi:10.1038/451135a

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Stem cell meeting 2008: in with the old, in with the new

Monya Baker & Natalie DeWitt

Although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.

Published online: 17 July 2008; doi:10.1038/stemcells.2008.108

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Smash the (Cell) State!

Bruce Goldman

A new quest for short cuts between specialized states could lay bare the machinery governing cell fate

Published online: 27 August 2008; doi:10.1038/stemcells.2008.115

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A chemical approach to stem-cell biology and regenerative medicine - pp338 - 344

Yue Xu, Yan Shi & Sheng Ding

Published online: 14 May 2008; doi:10.1038/nature07042

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