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| Open AccessExploring the pathways of drug repurposing and Panax ginseng treatment mechanisms in chronic heart failure: a disease module analysis perspective
- Chengzhi Xie
- , Ying Zhang
- & Na Lang
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| Open AccessTreatment of patients with carcinomas in advanced stages with 5-fluorouracil, folinic acid and pyridoxine in tandem
- David Machover
- , Wathek Almohamad
- & Emma Goldschmidt
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| Open AccessMagnetic resonance imaging of tumor response to stroma-modifying pegvorhyaluronidase alpha (PEGPH20) therapy in early-phase clinical trials
- Andrés M. Arias-Lorza
- , James R. Costello
- & Natarajan Raghunand
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| Open AccessA novel anti-LAG-3/TIGIT bispecific antibody exhibits potent anti-tumor efficacy in mouse models as monotherapy or in combination with PD-1 antibody
- Tongcheng Dai
- , Hao Sun
- & Binhua Lv
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| Open AccessPreparation of orodispersible tablets of bosentan using xylitol and menthol as dissolution enhancers
- Rania Mohamed Sakr
- , Abdelaziz El Sayed Abdelaziz
- & Gamal Mohamed El Maghraby
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| Open AccessDevelopment of a new affinity maturation protocol for the construction of an internalizing anti-nucleolin antibody library
- Rita Ribeiro
- , João N. Moreira
- & João Goncalves
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| Open AccessSynthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (Mpro)
- Deepika Geedkar
- , Ashok Kumar
- & Pratibha Sharma
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| Open AccessReal life experience on the use of Remdesivir in patients admitted to COVID-19 in two referral Italian hospital: a propensity score matched analysis
- Nicola Veronese
- , Francesco Di Gennaro
- & Annalisa Saracino
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| Open AccessIdentification of small molecules affecting the interaction between human hemoglobin and Staphylococcus aureus IsdB hemophore
- Monica Cozzi
- , Mariacristina Failla
- & Francesca Spyrakis
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| Open AccessLack of association between COVID-19 vaccines and miscarriage onset using a case-crossover design
- Irati Gastesi Orbegozo
- , Lucía Cea-Soriano
- & Consuelo Huerta-Álvarez
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| Open AccessBackground and clinical significance of biomarker-based patient enrichment in non-small-cell lung cancer drug development
- Kenji Harada
- & Shunsuke Ono
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| Open AccessFe3O4@Chitosan@ZIF-8@RVG29, an anti-glioma nanoplatform guided by fixed and activated by alternating magnetic field
- Mohammad-Nabil Savari
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| Open AccessTransfection of hypoxia-inducible factor-1α mRNA upregulates the expression of genes encoding angiogenic growth factors
- Jakub Wlodarczyk
- , Albert Leng
- & John W. Harmon
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| Open AccessNortriptyline hydrochloride, a potential candidate for drug repurposing, inhibits gastric cancer by inducing oxidative stress by triggering the Keap1-Nrf2 pathway
- Chunyang Zhu
- , Yangyang Lu
- & Weiwei Qi
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| Open AccessApomorphine is a potent inhibitor of ferroptosis independent of dopaminergic receptors
- Akihiko Miyauchi
- , Chika Watanabe
- & Hitoshi Osaka
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| Open AccessPacritinib inhibits proliferation of primary effusion lymphoma cells and production of viral interleukin-6 induced cytokines
- Yiquan Wu
- , Victoria Wang
- & Robert Yarchoan
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Article
| Open AccessQuercetin-crosslinked chitosan nanoparticles: a potential treatment for allergic rhinitis
- Dehong Mu
- , Li Zhou
- & Li Tian
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| Open AccessA pan-influenza monoclonal antibody neutralizes H5 strains and prophylactically protects through intranasal administration
- Anna L. Beukenhorst
- , Jacopo Frallicciardi
- & Jaap Goudsmit
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| Open AccessEvaluation of the antidermatophytic activity of potassium salts of N-acylhydrazinecarbodithioates and their aminotriazole-thione derivatives
- Anita Ciesielska
- , Aleksandra Kowalczyk
- & Paweł Stączek
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| Open AccessCrystallization kinetics of nanoconfined GeTe slabs in GeTe/TiTe\(_2\)-like superlattices for phase change memories
- Debdipto Acharya
- , Omar Abou El Kheir
- & Marco Bernasconi
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| Open AccessEdoxaban for stroke prevention in atrial fibrillation and factors associated with dosing: patient characteristics from the prospective observational ETNA-AF-China registry
- Xueyuan Guo
- , Juan Du
- & Jian Zhang
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| Open AccessFactors influencing pain medication and opioid use in patients with musculoskeletal injuries: a retrospective insurance claims database study
- Stefan Markus Scholz
- , Nicolas Fabrice Thalmann
- & Maria Monika Wertli
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| Open AccessEvaluation of a simplified pharmacovigilance tool for general practitioners: 5 years of insight
- A. Trenque
- , A. Rabiaza
- & X. Humbert
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| Open AccessRevealing the mechanistic interactions of profenofos and captan pesticides with serum protein via biophysical and computational investigations
- Kamonrat Phopin
- , Waralee Ruankham
- & Tanawut Tantimongcolwat
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| Open AccessA comparative study of clinical trial and real-world data in patients with diabetic kidney disease
- Samu Kurki
- , Viivi Halla-aho
- & Miika Koskinen
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| Open AccessA systematic review and network meta-analysis of pharmaceutical interventions used to manage chronic pain
- Ashish Shetty
- , Gayathri Delanerolle
- & Jian Qing Shi
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| Open AccessDynamics of technology emergence in innovation networks
- Martin Ho
- , Henry C. W. Price
- & Eoin O’Sullivan
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| Open AccessMeldrum’s acid assisted formation of tetrahydroquinolin-2-one derivatives a short synthetic pathway to the biologically useful scaffold
- Małgorzata Ryczkowska
- , Alicja Trocka
- & Sławomir Makowiec
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| Open AccessPRMT5 inhibition shows in vitro efficacy against H3K27M-altered diffuse midline glioma, but does not extend survival in vivo
- Elizabeth J. Brown
- , Leire Balaguer-Lluna
- & Gillian Farnie
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| Open AccessThe thrombin generation capability of the Chacma baboon (Papio ursinus): implications for haemostatic disease models
- J. Joubert
- , S. M. Meiring
- & W. J. Janse van Rensburg
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| Open AccessMyricetin suppresses traumatic brain injury-induced inflammatory response via EGFR/AKT/STAT pathway
- Chenxing Wang
- , Siguang Ouyang
- & Peipei Gong
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| Open AccessDual species sphingosine-1-phosphate lyase inhibitors to combine antifungal and anti-inflammatory activities in cystic fibrosis: a feasibility study
- Barbara Cellini
- , Gioena Pampalone
- & Claudio Costantini
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| Open AccessKTt-45, a T-type calcium channel blocker, acts as an anticancer agent by inducing apoptosis on HeLa cervical cancer cell line
- Nguyen Huy Du
- , Truong Thi Bich Ngoc
- & Dang Thi Phuong Thao
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| Open AccessCalcium phosphate ceramics combined with rhBMP6 within autologous blood coagulum promote posterolateral lumbar fusion in sheep
- Natalia Ivanjko
- , Nikola Stokovic
- & Slobodan Vukicevic
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| Open AccessInfluence of pneumatic transportation on the stability of monoclonal antibodies
- Pierre Coliat
- , Stéphane Erb
- & Xavier Pivot
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| Open AccessA Notch signaling-related lncRNA signature for predicting prognosis and therapeutic response in clear cell renal cell carcinoma
- Lulu Zhang
- , Yulei Li
- & Ke Zhu
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| Open AccessSelection, characterization and in vivo evaluation of novel CD44v6-targeting antibodies for targeted molecular radiotherapy
- A. C. L. Mortensen
- , H. Berglund
- & M. Nestor
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| Open AccessThe combination of Ephedrae herba and coixol from Coicis semen attenuate adiposity via glucocorticoid receptor regulation
- Ga-Ram Yu
- , Jai-Eun Kim
- & Won-Hwan Park
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| Open AccessSociodemographic characteristics of healthy volunteers along with their experience, attitude and concerns of clinical trials in Wuhan, China
- Hengyi Yu
- , Yinian Fang
- & Xiuhua Ren
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| Open AccessAntifibrotic effect of apremilast in systemic sclerosis dermal fibroblasts and bleomycin-induced mouse model
- Tomoaki Higuchi
- , Kae Takagi
- & Yasushi Kawaguchi
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| Open Access9-oxo-ODAs suppresses the proliferation of human cervical cancer cells through the inhibition of CDKs and HPV oncoproteins
- Kazumasa Mogi
- , Yoshihiro Koya
- & Hiroaki Kajiyama
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| Open AccessEfficacy and safety of polyethylene glycol loxenatide in type 2 diabetic patients: a systematic review and meta-analysis of randomized controlled trials
- Hazem Mohamed Salamah
- , Ahmed Marey
- & Mohamed Abd-Elgawad
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| Open AccessEfficacy and safety of eltrombopag in Chinese patients with refractory or relapsed severe aplastic anemia
- Hong Chang
- , Guangsheng He
- & Fengkui Zhang
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| Open AccessThe synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression
- Manman Deng
- , Jinshui Tan
- & Bing Xu
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| Open AccessThe quality monitoring of paracetamol medicament using a noninvasive microwave sensor
- Youness Zaarour
- , Fatimazahrae EL Arroud
- & M’hamed Drissi
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| Open AccessReproducibility in pharmacometrics applied in a phase III trial of BCG-vaccination for COVID-19
- Rob C. van Wijk
- , Laurynas Mockeliunas
- & Ulrika S. H. Simonsson
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| Open AccessLarge numbers of patients are needed to obtain additional approvals for new cancer drugs: A retrospective cohort study
- Charlotte Ouimet
- , Nora Hutchinson
- & Jonathan Kimmelman
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| Open AccessA novel retinoic acid receptor-γ agonist antagonizes immune checkpoint resistance in lung cancers by altering the tumor immune microenvironment
- Cheng-Hsin Wei
- , Lu Huang
- & Xi Liu
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| Open AccessGenomic and transcriptomic analysis of camptothecin producing novel fungal endophyte: Alternaria burnsii NCIM 1409
- Shakunthala Natarajan
- , Boas Pucker
- & Smita Srivastava