Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
Imaging studies use various techniques to visualize chemical systems. They rely on different parts of a given system yielding distinct responses to certain stimuli. The stimulus and response could be of optical origin such as in fluorescence microscopy, or magnetic, such as in NMR-based methods.
Bioimaging with photocontrol and multiplexing capability is vital for studying cellular interactions and dynamics, but multiplexed stimulated Raman scattering (SRS) imaging with reversible photocontrol is elusive. Here, the authors report SRS microscopy with Carbow-switch enabling multiplexed SRS imaging and tracking in live cells with reversible photocontrol and high spatiotemporal selectivity.
Near-infrared small molecule dyes are attractive in biophotonics, but generally rely on expanded aromatic structures to achieve this redshift. Here the authors report the use of a ground state antiaromatic strategy for 14 aminofluorene dyes, and their use in imaging kidney injury.
To determine the physiologically relevant oligomeric form of membrane proteins is extremely challenging. Now an elegant method of counting the oligomers in membrane proteins in near-native states is presented, using photobleaching and nanodiscs formed directly from cellular membranes.
Hyperspectral imaging can reveal important information without the need for staining. To extract information from this extensive data, however, new methods are needed that can interpret the spatial and spectral patterns present in the images.
Overcoming the challenges of plastic detection in plants has made it possible to transfer many of the lessons learned from plant–metal nanoparticle interactions to plastic nanoparticles.
Real-space imaging reveals how thin layers of ice grow. Although the basal structure of bulk ice is still observed in 2D ice, the edges exhibit different molecular arrangements.