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Optical techniques are methods that use light to probe or control matter. One prominent example is optical spectroscopy, which includes such methods as pump–probe spectroscopy, Raman spectroscopy and photoemission spectroscopy. Other examples of optical techniques are microscopy, interferometry, ellipsometry, optical tweezers, and imaging and sensing.
Here, the authors introduce Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) - a high-speed, non-destructive photoacoustic brain imaging technique that constructs 3D fluorescent maps of the brain and improves upon some of the limitations associated with traditional whole-brain optical imaging techniques.
Here, the authors use spot array illumination to enable mechanical-scan-free super-resolution microscopy with adjustable resolution and good effective field of view, demonstrating a platform for studying molecular interactions at the nanoscale.
The authors introduce ZS-DeconvNet, an unsupervised computational super-resolution method for multiple types of microscopes, that enhances image resolution by more than 1.5 times over the diffraction limit with 10 times lower fluorescence than regular superresolution imaging conditions.
Biosensing tools to detect multiple analytes in a high-throughput manner are still hindered by many limitations. Here, the authors present a label-free optofluidic platform integrating digital holography and microfluidics for analyte detection, allowing for the fingerprinting of heterogenous biological samples.
By combining spatial and frequency dispersive thin-film interfaces with deep residual learning, a miniature photodetector allowing the acquisition of high-dimensional information on light in a single-shot fashion is described.
Sub-cycle confinement and control of phase transitions in strongly correlated materials are theoretically demonstrated, potentially providing a way to investigate electron dynamics on timescales previously unattainable with these materials.