The Pharmacogenomics Journal TOP TEN

The top ten charts the articles that have been downloaded most often, in PDF format, from the The Pharmacogenomics Journal website in recent weeks. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

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August 2008

  1. A review of gene-drug interactions for nonsteroidal anti-inflammatory drug use in preventing colorectal neoplasia

    J T Cross, E M Poole and C M Ulrich

    doi:10.1038/sj.tpj.6500487

  2. The AmpliChip CYP450 test: cytochrome P450 2D6 genotype assessment and phenotype prediction

    M C Rebsamen, J Desmeules, Y Daali, A Chiappe, A Diemand, C Rey, J Chabert, P Dayer, D Hochstrasser and M F Rossier

    doi:10.1038/tpj.2008.7

  3. Molecular therapy in the microRNA era

    T Wurdinger and F F Costa

    doi:10.1038/sj.tpj.6500429

  4. The clinical role of genetic polymorphisms in drug-metabolizing enzymes FREE

    D Tomalik-Scharte, A Lazar, U Fuhr and J Kirchheiner

    doi:10.1038/sj.tpj.6500462

  5. Pharmacogenetics of warfarin: current status and future challenges

    M Wadelius and M Pirmohamed

    doi:10.1038/sj.tpj.6500417

  6. Characterization of novel CYP2C8 haplotypes and their contribution to paclitaxel and repaglinide metabolism

    C Rodríguez-Antona, M Niemi, J T Backman, L I Kajosaari, P J Neuvonen, M Robledo and M Ingelman-Sundberg

    doi:10.1038/sj.tpj.6500482

  7. Pharmacogenetic profiling in patients with advanced colorectal cancer treated with first-line FOLFIRI chemotherapy

    A Ruzzo, F Graziano, F Loupakis, D Santini, V Catalano, R Bisonni, R Ficarelli, A Fontana, F Andreoni, A Falcone, E Canestrari, G Tonini, D Mari, P Lippe, F Pizzagalli, G Schiavon, P Alessandroni, L Giustini, P Maltese, E Testa, E T Menichetti and M Magnani

    doi:10.1038/sj.tpj.6500463

  8. Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity FREE

    M Ingelman-Sundberg

    doi:10.1038/sj.tpj.6500285

  9. Overview of the pharmacogenomics of cigarette smoking

    M K Ho and R F Tyndale

    doi:10.1038/sj.tpj.6500436

  10. Epidermal growth factor receptor polymorphisms and clinical outcomes in non-small-cell lung cancer patients treated with gefitinib

    G Liu, S Gurubhagavatula, W Zhou, Z Wang, B Y Yeap, K Asomaning, L Su, R Heist, T J Lynch and D C Christiani

    doi:10.1038/sj.tpj.6500444

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