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Hepatology

Understanding liver repair through space and time

By integrating spatially resolved single-cell RNA sequencing (scRNA-seq) and Stereo-seq data, two studies in this issue characterize molecular signatures of liver cell types and their interactions in homeostasis, damage, repair and regeneration.

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Fig. 1: Spatial insights into liver responses in homeostasis, damage, repair and regeneration.

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Acknowledgements

E.R.A. acknowledges support from Karolinska Institutet Career Ladder (2-195/2021), the Swedish Research Council (2023-01847), the Swedish Foundations' Starting Grant/The Ragnar Söderberg Foundation (S11/20) and the Knut and Alice Wallenberg Foundation (2020,0109). L.B. acknowledges funding from the European Union’s Horizon Europe research and innovation programme under the Marie Skłodowska-Curie grant agreement no. 101057846.

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Correspondence to Emma R. Andersson.

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Belicova, L., Van Hul, N. & Andersson, E.R. Understanding liver repair through space and time. Nat Genet 56, 740–742 (2024). https://doi.org/10.1038/s41588-024-01741-7

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