Abstract
Collaboration can be challenging; nevertheless, the emerging successes of large, multi-partner, multi-national cooperatives and research networks in the biomedical sector have sustained the appetite of academics and industry partners for developing and fostering new research consortia. This model has percolated down to national funding agencies across the globe, leading to funding for projects that aim to realise the true potential of genomic medicine in the 21st century and to reap the rewards of 'big data'. In this Perspectives article, the experiences of the RA-MAP consortium, a group of more than 140 individuals affiliated with 21 academic and industry organizations that are focused on making genomic medicine in rheumatoid arthritis a reality are described. The challenges of multi-partner collaboration in the UK are highlighted and wide-ranging solutions are offered that might benefit large research consortia around the world.
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RA-MAP, molecular immunological landscapes in early rheumatoid arthritis and healthy vaccine recipients
Scientific Data Open Access 09 May 2022
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Change history
24 January 2018
In the version of this article originally published, the name of one of the authors, Peter Schulz-Knappe, was incorrectly given as Peter Schulze-Knappe. In addition, Mark Coles and James Butler were erroneously omitted from the list of members of the RA-MAP Consortium. These errors have now been corrected in the PDF and HTML versions of the article.
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Acknowledgements
The programme of research described in this Perspectives article was funded by the Medical Research Council (MRC), UK. The RA-MAP Consortium would particularly like to thank members of the MRC Immunity and Inflammation Stratified Medicine Steering Group and officers of the MRC, who have supported the work of the RA-MAP Consortium with unbridled enthusiasm.
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A.P.C., M.R.B. and J.D.I. wrote the manuscript. A.P.C., S.B., F.B.-C. and A.W.P. researched data for the article. A.P.C., M.R.B., A.B., M.B., S.B., F.B.-C., B.A.F., C.S.G., P.E., M.E.R., N.G., R.H., S.H., M.F.M., I.B.M., S.R., A.W.P., F.P., D.P., R.R., A.R., M.A.S., D.S., B.T. and J.D.I. provided substantial contributions to discussions of content. A.P.C., M.R.B., A.B., S.B., F.B.-C., C.C., B.A.F., C.S.G., M.E.R., N.G., R.H., S.H., S.K., M.L., C.L., M.F.M., I.B.M., C.M.M., G.P., S.R., A.W.P., F.P., D.P., A.R., P.S.-K., M.A.S., D.S., P.C.T., B.T., W.T., D.V. and J.D.I. reviewed and/or edited the manuscript before submission.
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A.P.C. declares that he has acted as a consultant for or received honoraria from BMS, Eisai, GSK, Janssen and Roche. For a full list of competing interests for all co-authors, see Supplementary information S6 (table).
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FURTHER INFORMATION
PowerPoint slides
Supplementary information
Supplementary information S1 (figure)
The RA-MAP Consortium (PDF 95 kb)
Supplementary information S2 (figure)
The RA-MAP Research Programme (PDF 849 kb)
Supplementary information S3 (figure)
Project management and reporting lines (PDF 227 kb)
Supplementary information S4 (figure)
RA-MAP core technologies (PDF 73 kb)
Supplementary information S5 (figure)
Managing 'big data' (PDF 800 kb)
Supplementary information S6 (table)
Contributing authors and their competing interests (PDF 153 kb)
Supplementary information S7 (box)
RA-MAP Consortium Membership (2012 – current) (PDF 266 kb)
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Cope, A., Barnes, M., Belson, A. et al. The RA-MAP Consortium: a working model for academia–industry collaboration. Nat Rev Rheumatol 14, 53–60 (2018). https://doi.org/10.1038/nrrheum.2017.200
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DOI: https://doi.org/10.1038/nrrheum.2017.200
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