Understanding normal hematopoiesis is critical to understanding disease. Technological advances are driving insight into human hematopoiesis at unprecedented resolution. Integrating ‘-omics’ datasets with machine learning has yielded a high-resolution map of primary human bone marrow hematopoietic progenitor cells that supports the study of immune cell development, as well as the origins of disease.
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K.M.B. declares that they have consulted for Agios and Novartis and have received research funding from Syndax Pharmaceuticals. These contributions are unrelated to the subject material discussed in this article.
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Bernt, K.M. Mapping human hematopoiesis. Nat Immunol 25, 590–591 (2024). https://doi.org/10.1038/s41590-024-01793-1
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DOI: https://doi.org/10.1038/s41590-024-01793-1