Abstract
Despite abundant scientific evidence supporting immunization benefits, vaccine hesitancy remains a significant global health concern, particularly during public health crises. Exploring public attitudes towards vaccination is crucial. This study aimed to develop and validate a tailored Public Vaccination Attitudes Scale specifically under the unique circumstances of a public health crisis. A psychometric evaluation was conducted using a cross-sectional study during the peak of a major public health crisis. The scale was developed and its psychometric properties validated using three approaches: (1) generating the item pool through literature research and focus group discussions; (2) assessing the items through expert consultation; and (3) evaluating construct validity, content validity, and internal consistency reliability through exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Data from a total of 3921 respondents were randomly divided into two subsets, one for EFA (n = 1935) and the other for CFA (n = 1986). A 22-item draft scale with five factors was created after literature research and focus group discussion. The content validity of this scale ranged between 0.88 and 1.00. EFA showed a 17-item scale with four factors (Cronbach’s α > 0.7) accounting for 68.044% of the total variance. CFA showed that the values of the fit indices, including convergent validity and discriminant validity, were excellent or acceptable. The overall Cronbach’s α was 0.874, and each factor ranged from 0.726 to 0.885. This study introduces a valuable tool for assessing vaccination attitudes during public health crises, aiding researchers, policymakers, and nurses in combating vaccine hesitancy. Emphasizing the importance of fostering vaccine acceptance, it enhances disease control during emergencies, contributing to the knowledge needed for more effective public health strategies and crisis responses
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Introduction
Public health crises, often characterized by their sudden and unpredictable nature, exert a profound impact on societies and global healthcare systems. These crises can be triggered by various factors, including infectious disease outbreaks, natural disasters, or unforeseen events. During such crises, the public’s stance on vaccination assumes a pivotal role in the management and control of diseases1.
Immunization stands as one of the most successful and cost-effective health interventions against infectious diseases, particularly in the context of epidemic disease prevention and control2. Research has shown the significant advantages of vaccination, encompassing decreased disability, hospital admissions, healthcare costs, and mortality rates3,4,5. However, recent years have witnessed a concerning decline in public trust in vaccines, accompanied by rising rates of vaccine hesitancy6,7. Vaccine hesitancy, shown as reluctance or refusal to get vaccinated despite vaccines being available, is an intriguing phenomenon, especially during crises such as the COVID-19 pandemic. It has gained more attention because it can weaken public health efforts8. Even before the onset of the COVID-19 pandemic, the World Health Organization (WHO) ranked hesitation about vaccines as one of the top ten global health threats9,10.
Understanding global drivers of vaccine acceptance is a pressing concern11. Vaccine acceptance, a complex interplay of individual characteristics, social environment, and cross-cultural differences4,12, impacts disease risk perception, vaccine attitudes, and overall demand among the population. High vaccination coverage is crucial, especially during outbreaks of emerging infectious diseases13. Misconceptions about vaccine safety and disease risks will lead to hesitancy or refusal14. Comprehending the intricate interplay of factors impacting vaccine acceptance aids in making well-informed decisions for public health practitioners, policymakers, and researchers.
In 2017, Martin and Petrie developed the Vaccination Attitudes Examination Scale (VAX) through literature review and focus group data analysis15. It’s a concise and comprehensive tool focused on identifying individuals with vaccination reluctance, targeting four key factors: mistrust of vaccine benefits, concerns about unforeseen future, worries about commercial profiteering, and preference for natural immunity. The VAX has undergone rigorous testing of its psychometric properties in several countries, including Hebrew4, Spanish16, French17, Colombian18, and Romanian19. And the VAX has also been adapted to specially assess attitudes towards vaccines against COVID-194,20,21,22. And the VAX has consistently shown good reliability and validity. However, notable fluctuations in vaccine acceptance rates have been observed, especially during the COVID-19 period.
Significant changes in vaccination attitudes have been observed across the pandemic.98.7% of participants received at least one dose of a COVID-19 vaccine23, with 9% refusing vaccination and 30.8% expressing hesitancy24. Studies have also shown that 46.6% of participants displayed a positive attitude towards COVID-19 vaccination uptake25, while 45.6% were hesitant about COVID-19 vaccines22. Concerns regarding unexpected future effects have increased, indicating higher perceived risks related to vaccination, and a more deliberative information-seeking approach among participants26. Vaccine acceptance attitudes are influenced by sociodemographic factors like gender, age, occupation, past vaccination success, and education level23,24,25,26, which are linked to participants' perception of disease risk. When perceiving low disease risk, individuals may hesitate to accept vaccination risks27.
Significant fluctuations in vaccination attitudes highlight the limitations of VAX and other related measurement tools during major public health events. Attitudes toward vaccination are influenced by situational factors, particularly during uncertain Major Public Health Crisis events. The balance between individuals' risk perception of the event and the perceived safety of vaccines primarily determines vaccine acceptance attitudes. Although the adjusted VAX assessed acceptance attitudes and influencing factors during COVID-19, the focus was primarily on vaccine safety, neglecting individuals’ risk perception of the crisis event itself. When personal safety is not directly threatened, people tend to prioritize risk avoidance over vaccine acceptance1. Therefore, integrating risk perception factors into the scale is necessary. Additionally, vaccination attitudes are influenced by multicultural factors. Despite cultural adjustments in numerous studies, the accuracy of measurement depends on whether the content reflects the genuine needs of specific cultural populations. Thus, integrating specific cultural contexts is necessary to establish reliable measurement indicators. Furthermore, during a Major Public Health Crisis, rapid and decisive response measures are essential. Measurement tools must have concise and rapid identification capabilities, as well as universality across different populations. Given the differences in vaccine acceptance attitudes across various countries and cultural backgrounds. Thus, the purpose of this study is to develop the Public Vaccination Attitudes Scale to assess and measure public attitudes towards vaccination during a major public health crisis.
This study contribute to addressing the critical gap in our understanding of vaccination attitudes amidst public health crises and provide a validated instrument for evaluating these attitudes. By doing so, it seeks to contribute to the development of more effective strategies for vaccine acceptance, ultimately improving disease control and response efforts during times of crisis.
Scale development
Three approaches were employed in developing the Vaccination Attitudes Amidst a Major Public Health Crisis and determining its psychometric properties3: (1) generation of an item pool; (2) expert consultation; and (3) factor analysis.
Generation of an item pool
Content analysis of the literature and focus group discussion were conducted at this stage24. The items of the scale were obtained by reviewing the literature on measurement tools or questionnaires that could be related to vaccination and conducting focus group discussions covering topics such as factors that affect acceptance or refusal of vaccination and concerns about vaccination. A 22-item draft scale was created with 5 factors, recognition, environment, value, security and knowledge, with higher scores representing positive acceptance attitudes. Responses were provided on a 5-point scale (1 = strongly disagree to 5 = strongly agree). Items 4, 5, 6, 8, 9, 12, 13, 14 and 20 were scored in the opposite order. The overall score ranged from 22 to 110 points.
Expert consultation
Item evaluation was performed by the expert consultation method. Inclusion criteria were as follows: ① Expertise in hospital management, disaster management, public health management, vaccine research, and participation in public health prevention and control; ② greater than 5 years of professional experience; ③ bachelor’s degree, associate senior title, or above; and ④ voluntary participation. Experts who could not be contacted electronically were excluded. A draft scale was sent to 20 experts at this stage, with 18 experts responding. If no response was received within 2 weeks, we considered it a lack of time or interest and discontinued contact. The experts classified each item of the scale as ‘unimportant', ‘important but needs correction', and ‘important'.
Expert Information: ① Age ranged from 30 to 60 years old, with one expert above 60 years old.; ② 13 (72.2%) had 31–40 years of experience, 2 (11.1%) had 21–30 years, 2 (11.1%) had 11–20 years, and only 1 (5.6%) had 5–10 years; ③ 3 (16.7%) had undergraduate degrees, 4 (22.2%) had master’s degrees, and 11 (61.1%) had doctoral degrees.; ④ 4 (22.2%) were head nurses in hospitals, 4 (22.2%) were hospital managers, 2 (11.1%) worked in public health management, 2 (11.1%) were involved in vaccine research, 5 (27.8%) were engaged in combating a public health crises, and 1 (5.6%) was a professor of statistics.; ⑤ the research team comprised 1 PhD student and three master’s students. In both rounds of expert consultation, the judgment coefficient (Ca) was 0.79, the familiarity coefficient (Cs) was 0.87 and 0.95 respectively, and the expert authority coefficient (Cr) was 0.83 and 0.87. A Cr value ≥ 0.7 is generally considered acceptable for reliability28. The consulted experts demonstrated a high level of authority on the issues, ensuring highly reliable results.
The recovery rate, content validity index (CVI), item content validity index (I-CVI), scale-level S-CVI, average S-CVI (S-CVI/Ave) and universal agreement S-CVI (S-CVI/UA) were calculated.
The consensus coefficients for the two rounds were 90% and 93.3% respectively. All I-CVI data were greater than 0.8828. The experts' active participation and efficiency in both rounds demonstrate their keen interest in the study and reflect heightened global awareness and concern stemming from significant public health events like COVID-19. Vaccine acceptance plays a crucial role in safeguarding global health, thus making research on vaccination attitudes a prominent focus and trend.
In the first round of expert consultation, one suggestion was added: “Since the vaccine is free, I’m willing to take it.” Additionally, five recommendations were modified. No items were added to or removed from the scale, but eleven items underwent corrections to rectify grammatical and spelling errors and enhance statement clarity. After the modifications, Kendall’s W coefficient was 0.136 (P < 0.05), S-CVI/UA was 0.66, and S-CVI/Ave was 0.97. Following these revisions, we proceeded with the second round of expert consultation. The Kendall’s W coefficient for the second round of Delphi consultation was 0.171 (P < 0.001). S-CVI/UA was 0.87, and S-CVI/Ave was 0.99. The 22-item scale was created according to expert suggestions. All indicators showed that the scale exhibited relatively satisfactory content validity29 and was recognized by experts from a professional point of view.
Factor analysis
EFA and CFA were performed to determine the construct validity together with the reliability of the scale, constituting the psychometric evaluation.
Item analysis and homogeneity tests were used to filter the initial items. This study adopted the extreme group method to analyse items. The difference between the top 27% and the bottom 27% of the total score of the questionnaire was compared by t tests. If P > 0.05, the item was deleted. We compared the high group (top 27%, total score ≥ 155 points) with the low group (bottom 27%, total score ≤ 82 points), and all items achieved significant P values (P < 0.001). In the homogeneity test, the correlation coefficient (R value) between items and the whole questionnaire was higher than 0.4, indicating that the acceptance attitudes measurement tool developed in this study exhibited a high level of homogeneity.
Kaiser–Meyer–Olkin (KMO) and Bartlett’s Test of Sphericity were performed to assess the suitability of the questionnaire for exploratory factor analysis. A KMO value > 0.80 or a P value of Bartlett’s Test < 0.05 indicates adequate sample size and suitability of variables for factor analysis. A further factor structure was developed with factors whose Cronbach’s α was > 0.7 and item loading was > 0.4, which were then selected as the new structure. Confirmatory factor analysis (CFA) was used to test whether this factor structure was suitable, and convergent validity and discriminant validity were explored. Cronbach’s α coefficient was used to assess the reliability of the scale.
Methods
Study design
The research adopted a cross-sectional design and adhered to the STROBE cross-sectional reporting guidelines25. Participation in the study was voluntary and anonymous, with informed consent obtained and documented via electronic signature. All collected data were treated confidentially and utilized solely for research purposes.
Data collection
Data collection occurred from June to August 2021, facilitated by a Sojump online survey, accessible through the Questionnaire Star survey website, the largest online survey platform in China, catering to research institutions' online questionnaire design and survey needs. Employing the self-selection online survey method, a nonprobability sampling approach26, participants were recruited via social network links. The study’s target population comprised adults aged 18 years or older residing in mainland China.
Quality control
Throughout the investigation, two researchers were tasked with overseeing the completion of questionnaires and gathering adjustment recommendations via the website. Subsequently, upon concluding the investigation, we meticulously screened the data to ensure its accuracy.
Floor and ceiling effects
Among the participants, 8% scored the lowest possible score for the survey, and 5% scored the highest possible score. We introduced reverse items to address ceiling or floor effects. Additionally, the diverse participant pool and random data division into two parts for exploratory and confirmatory factor analyses also helped alleviate these effects to some extent.
Participants
A total of 4021 respondents participated in the survey using the Questionnaire Star survey website. However, 100/4021 (2.5%) of the questionnaires were removed from the sample according to the following exclusion criteria: (a) the surveys were incomplete; (b) the questionnaires were completed by respondents under 18 years of age; (c) the respondents did not consent using the first two questions; and (d) the same response options were chosen consistently. Ultimately, 3921 eligible surveys were analysed.
Statistical analysis
Data were analysed by IBM SPSS 20.0 for Windows and AMOS, and P < 0.05 was considered statistically significant in two-tailed tests. The general characteristics were described by means (SD) or frequencies for categorical items. Concordance among the experts was assessed using Kendall’s W analysis. The structural validity of the scale was assessed using EFA and CFA. Cronbach’s alpha was used for reliability analysis.
Ethics approval and consent to participate
The West China Hospital of Sichuan University Biomedical Research Ethics Committee approved the study (ethics number: 2021-992). All participants gave electronic informed consent for the participation. The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and the Helsinki Declaration of 1975, as revised in 2008. Participation in the study was anonymous.
Results
Demographic characteristics
The study ensured the representativeness of survey participants by encompassing all adults aged 18 years and above nationwide. Participants had a mean age of 32.58 years (SD = 11.85; range = 18–85). Among the respondents, 77.5% were female (n = 3073), and 94.8% were ethnically Han (n = 3716). The highest educational level of 28.1% was a junior college degree (n = 1100). Almost half were married (51.3%). A total of 75.8% had a nonmedical background (2971), and 50.1% reported that their families had a medical background (1966). A total of 31.9% came from a large city, and 31.5% were from a mid-sized city. A total of 29.6% had an average family income (CNY) ≤ 5000 (Table 1).
Item analysis and item homogeneity test
The questionnaire was randomly divided into two parts, one for EFA (n = 1935) and the other for CFA (n = 1986). The results of item analysis and item homogeneity were based on EFA. All items achieved significant P values (P < 0.001). In the homogeneity test, the correlation coefficient (R value) between items and the whole questionnaire was higher than 0.4; the value for Item 10 was 0.395, so it was deleted. The remaining 21 items were included in the EFA (Table 2).
Structural validity and reliability
Principal component analysis and the promax method were used in EFA. Factors with eigenvalues above one were selected, while items with a maximum factor loading value < 0.4 and those with double loading were deleted if the factor load value of the main item was at least 2 times that of the minor factor as the entry inclusion criterion. The KMO value was 0.888, and Bartlett’s test of sphericity was significant (X2 = 17999.208, df = 136, P < 0.001), the data were ideal for factor analysis. The cumulative contribution rate was 68.044% indicated satisfactory construct validity.
A new four-factor structure was formed in Table 3. The Cronbach’s α of all factors was above 0.874, and the coefficients of recognition, environment, value and safety were 0.885, 0.839, 0.882 and 0.726, respectively. The CFA results were as follows: CMIN/df = 7.518, RMR = 0.042, GFI = 0.9530, AGFI = 0.0.935, NFI = 0.958, RFI = 0.949, IFI = 0.964, CFI = 0.964 and RMSEA = 0.056 (Fig. 1, Tables 4 and 5). All values of GFI, AGFI, NFI, RFI, IFI, TFI and CFI were above 0.930. CMIN/df was greater than 3, RMSEA was less than 0.08, and RMR was less than 0.05, which indicated that the four-factor structure fit excellently31. When the sample size exceeds 1000, the chi-square value of the model will also increase, so CMIN/DF was not strictly considered32. All values of composite reliability (CR) of the four dimensions were greater than 0.733, which means they achieved the required level. The values of average variance extracted (AVE) in Factors 2 and 4 were below but close to 0.5, indicating adequate construct reliability and adequate convergent validity34. For Factors 2 and 4, although the AVE value was less than 0.5, the other indicators were satisfactory; the CR values of the two factors were 0.835 and 0.747, respectively. Therefore, the factors were kept in the acceptance attitudes to vaccines scale. The square between the respective constructs was less than the square of AVE for the construct that achieved the discriminant validity of the acceptance attitudes towards vaccines.
Discussion
In this study, we created a scale for evaluating acceptance attitudes towards vaccination amidst a major public health crisis. A 17-item scale with four factors was confirmed: recognition (5 items), environment (6 items), value (3 items) and safety (3 items) formed the public acceptance attitudes towards vaccination scale.
Factor one was named ‘recognition’ and included 5 items (A15/A16/A17A18/A19). The Cronbach’s α value was 0.885, and item loading ranged from 0.528 to 0.898. They were all recommended and approved by authoritative institutions or trusted individuals, including the country, work units, medical staff, and family/friends. The price of vaccines plays a significant role in determining their affordability for individuals and serves as a primary factor in assessing vaccine acceptance. Recognition facilitates the rapid identification of factors influencing vaccine confidence and the establishment of manageable response strategies during public health emergencies. Confidence is a key influencing factor in vaccine hesitancy35, and recommendations from trusted individuals in the community can enhance individuals’ confidence in vaccine acceptance.
A research reveals that 87.09% of respondents deemed their doctor’s recommendation as crucial for decision-making36. Recognition also significantly influenced individuals' vaccination attitudes, serving as a cornerstone in fostering confidence and trust in the vaccination process. This contributed to increased vaccine acceptance amid major public health crises, as individuals prioritize safeguarding themselves and others from disease risks. However, the sudden and unpredictable nature of such crises can lead to fluctuations in vaccine acceptance. This is attributed to asymmetrical information regarding vaccines, where initial misinformation or incomplete knowledge may foster misunderstandings and resistance towards vaccination, fueling panic and distrust37. Yet, as validation of vaccine safety increases, public acceptance gradually improves. Therefore, recognition can swiftly identify controllable factors that foster positive attitudes towards vaccine acceptance, effectively mitigating the challenges posed by public crises.
Factor 2 was named ‘environment’ and included 6 items (A5/A6/A8/A9/A13/A14). The Cronbach’s α value was 0.839, and item loading ranged from 0.491 to 0.756. This factor represents the perception of the current risk of infectious disease outbreaks; if individuals perceive risk, they will behave to mitigate the risk. Vaccination is the most important response measure. Accordingly, people will exhibit positive response behaviour; otherwise, their behaviour involves hesitation and a lack of acceptance of the vaccine. A global survey indicates that individuals' attitudes towards vaccine acceptance have been influenced by the information disseminated through various social media platforms and the severity of COVID-19 cases38. Environmental experience is a crucial external factor determining individual vaccine acceptance39. According to surveys, there is a significant contrast in individuals’ attitudes towards vaccine acceptance during and after the COVID-19 pandemic38,40. When individuals are experiencing a major public health crisis like COVID-19, their perception of the imminent threat to life and health is deeper and more genuine, providing a more objective reflection of public attitudes towards vaccine acceptance or refusal. This differs from conventional factors influencing vaccine acceptance attitudes. However, after this period, vaccine acceptance attitudes are influenced by various sources of information, such as media reports and individual experiences. Therefore, the measurement of the environmental dimension in this study provides a more authentic and objective reflection of the current situation.
Factor 3 was named ‘value’ and included 3 items (A1/A2/A3). The Cronbach’s α value was 0.882, and item loading ranged from 0.781 to 0.8906. This factor captured opinions about the role and value of the vaccine. Whether an individual accepts a vaccine depends mainly on whether the vaccine can play a role in reducing infection. If the vaccine can reduce the infection rate and the rate of serious disease after infection, then the vaccine plays a role and can be positively recognized and accepted. The value dimension acts as a direct determinant of individual vaccine acceptance attitudes and also indirectly reflects individuals' health literacy regarding vaccines. Higher levels of health literacy regarding vaccines indicate a deeper understanding of the role and importance of vaccines in disease prevention. Conversely, lower levels of perceived value may signify knowledge gaps or misconceptions about vaccines, resulting in hesitancy or reluctance to accept vaccination. Understanding and addressing the factors influencing perceptions of vaccine value are essential for promoting vaccine acceptance and effectively addressing vaccine hesitancy41.
Factor 4 was named ‘safety’ and included 3 items (A4/A12/A20). The Cronbach’s α value was 0.726, and item loading ranged from 0.600 to 0.789. The three items were “quality and safety”, “protective effect”, “quality of the vaccine produced by the manufacturer” and all involved the theme of security. The most important consideration for an individual when getting vaccinated is the safety of the vaccine. The safety and efficacy of the vaccine are reasons for an individual to overcome hesitation, which is also in line with medical decision-making behaviour theory42. Safety is a key factor shaping individuals’ vaccine acceptance, especially during unforeseeable public health crises. When individuals are unsure about vaccine efficacy, safety becomes their primary concern43. Hence, strategies addressing safety concerns and providing transparent, accurate vaccine safety information are crucial for improving vaccination attitudes and uptake rates.
The scale is a unique and practical tool for assessing vaccination attitudes during a major public health crisis, providing distinct advantages and practical significance. Although a multitude of tools exist for assessing vaccine acceptance attitudes, including those tailored to COVID-19 vaccines, and extensive research has examined diverse predictive factors such as gender, age, education level, and economic development35,36,37,38,39,40,41, the emphasis of these investigations predominantly centers on uncontrollable variables. Addressing uncontrollable factors poses challenges for short-term resolution. During major public health crises, there is an urgent imperative to promptly tackle controllable factors that impact vaccine acceptance attitudes. The four dimensions of our research instrument are well-suited for evaluating vaccine acceptance attitudes amidst major public health crises. Recognition, environment, safety and value were the main factors in vaccine acceptance decision-making. Whether an individual makes a decision depends on both intrinsic and extrinsic factors centred on vaccine safety. Internal factors include vaccine safety and value, namely, whether the vaccine plays a reliable role. External factors include the urgency of the environment and the degree of recognition of the vaccine. Internal and external factors also involve weighing the pros and cons of vaccine acceptance or refusal. This can provide not only factors for public vaccine acceptance decision-making but also the weight of the factors to provide a basis for screening and decision-making for vaccine acceptance in different environmental settings.
The initial 5 items (A7/A10/A11/A21/A22/), which were about responses to individual knowledge of vaccines, were deleted and excluded from statistical analysis based on numerical exclusion criteria. In addition to statistical reasons, we analysed other possibilities. One was based on the realistic principle that individuals care more about the function and safety of vaccines than they do about the knowledge of vaccines. Previous studies have considered vaccine knowledge to be important36, but for people from non-medical backgrounds, especially in emergency settings, the safety and value of vaccines are considered more important. The other possibility is that individuals are very knowledgeable about vaccines because vaccines have been used successfully against many viruses throughout history. Finally, a statistical descriptive summary of several items showed that the scores ranged from 3.93 ± 0.88 to 4.66 ± 0.66, which were all relatively high. This indicated that knowledge of vaccines was not the main consideration for deciding whether to accept vaccines, but this specific explanation needs further research and analysis.
Limitations
This study has several limitations. Firstly, the use of an online survey platform, while convenient and efficient, may introduce selection bias and raise concerns about response accuracy and misinterpretation of questions. Additionally, the inability to verify respondent identity online may compromise data validity. However, it’s worth noting that these limitations may not have significantly impacted the results. Secondly, the study exclusively utilized quantitative research methods to explore vaccination acceptance attitudes, suggesting a need for future research to incorporate qualitative approaches. Thirdly, retest reliability was not conducted, but it is planned for inclusion in a subsequent study. Lastly, the large sample size may potentially introduce ceiling or floor effects. To address this, we diversified sample sources and partitioned the dataset for exploratory and confirmatory factor analyses, aiming to mitigate these effects to some extent.
Conclusions
We developed a scale for measuring acceptance attitudes towards vaccination and validated it with a relatively adequate sample size. This scale is a 17-item scale with 4 factors and excellent reliability and validity, making it acceptable and useful. It provides an effective evaluation tool for assessing whether individuals have adopted vaccination behaviour. The scale serves as a rapid assessment tool for identifying public vaccination acceptance attitudes, particularly during major public health crises. It enables healthcare practitioners to recognize and comprehend the key factors influencing vaccine acceptance attitudes, facilitating targeted health education and promotional campaigns aimed at altering public attitudes and behaviors, thereby promoting vaccination and reducing hesitancy. The dimensions assessed by the scale represent critical and controllable factors that the public primarily considers during major public health crises. Consequently, it can guide health policymakers in promptly understanding public attitudes toward vaccine acceptance and formulating more targeted and effective vaccination policies to enhance vaccination rates across diverse demographic groups. Additionally, healthcare professionals can employ the scale periodically to assess dynamic trends in vaccine acceptance attitudes and adjust relevant promotional and educational strategies in a timely manner, ensuring the effective implementation of vaccination activities. We look forward to witnessing the widespread application of this scale in practice and its contribution to addressing current and future global health challenges. Meanwhile, the scale can be used as a necessary part of the emergency plan system for screening and decision-making. The four dimensions in the scale contribute to building a knowledge system and model of vaccine acceptance, thereby enhancing strategies for major public health crisis prevention and control. Finally, this scale can be widely applied and tested in practice, contributing to addressing current and future global health challenges.
Data availability
The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request.
Abbreviations
- CMIN/df:
-
Chi-square/df
- RMR:
-
Root mean square residual
- GFI:
-
Goodness-of-fit index
- AGFI:
-
Adjusted goodness-of-fit index
- NFI:
-
Normed fit index
- RFI:
-
Relative fit index
- IFI:
-
Incremental fit index
- CFI:
-
Comparative fit index
- RMSEA:
-
Root mean square error of approximation
- VAX:
-
Vaccination Attitudes Examination Scale
- COVID-19:
-
Coronavirus disease 2019
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Acknowledgements
We extend our gratitude to all the school administrators, community workers, and volunteers for their invaluable contributions to the successful implementation of this study. Additionally, we would like to express our sincere appreciation to the reviewers and editors for their insightful comments and suggestions, which greatly contributed to the refinement of this manuscript. Their feedback has been instrumental in enhancing the quality and clarity of our research findings.
Funding
This work was supported by the National Natural Science Foundation of China (Grant: 71871147), the Science and Technology Department of Sichuan Province Project (Grant: 2021YJ0013; 2023JDGD0035).
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L.C. wrote the main manuscript text, X.X. and J.K. acquired and analyzed data, F.Z. revised and supervised the manuscript. All authors reviewed the manuscript. All authors read and approved the final manuscript.
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Cheng, L., Kong, J., Xie, X. et al. A psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis. Sci Rep 14, 10250 (2024). https://doi.org/10.1038/s41598-024-61028-z
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DOI: https://doi.org/10.1038/s41598-024-61028-z
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