Abstract
Hybrid systems that integrate synthetic materials with biological machinery offer opportunities for sustainable and efficient catalysis. However, the multidisciplinary and unique nature of the materials–biology interface requires researchers to draw insights from different fields. In this Perspective, using examples from the area of N2 and CO2 fixation, we provide a unified discussion of critical aspects of the material–microbe interface, simultaneously considering the requirements of physical and biological sciences that have a tangible impact on the performance of biohybrids. We first discuss the figures of merit and caveats for the evaluation of catalytic performance. Then, we reflect on the interactions and potential synergies at the materials–biology interface, as well as the challenges and opportunities for a deepened fundamental understanding of abiotic–biotic catalysis.
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Acknowledgements
C.L. acknowledges support from the National Institute of Health (R35GM138241 and R01ES032668), the Sloan Research Fellowship from the Alfred P. Sloan Foundation and the Jeffery and Helo Zink Endowed Professional Development Term Chair. Whereas the manuscript was written by human researchers, the final text was fed to ChatGPT to check for grammar and spelling issues.
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X.G. wrote the initial draught. All the authors contributed to the discussion, reviewing and editing of the manuscript.
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Guan, X., Xie, Y. & Liu, C. Performance evaluation and multidisciplinary analysis of catalytic fixation reactions by material–microbe hybrids. Nat Catal (2024). https://doi.org/10.1038/s41929-024-01151-2
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DOI: https://doi.org/10.1038/s41929-024-01151-2