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  • Climate change and ecological emergencies threaten life on Earth. This creates a distress that is in danger of being pathologized and dismissed. We examine how such feelings are rational and underpinned by instinctive compassion for the environment and each other. We must respond by supporting people to act with their full potential, amidst systemic and government failures.

    • Elizabeth Marks
    • Caroline Hickman
    Comment
  • Sex and gender play an important role in mental health. Clinical and preclinical research for novel treatments need to take this serious matter under consideration. The development of safe and effective treatments for specific populations can be achieved only with enhanced and targeted funding that will generate robust and reliable data.

    • Christina Dalla
    Comment
  • Climate change is affecting mental health in all communities, especially in young people. It is critical that we consider how to support young people affected by climate change anxiety and the possibilities of looking forward to supporting them.

    • Janis Whitlock
    Comment
  • In this Comment, Patwary et al. discuss the mental health needs of the Turkey–Syria earthquake survivors from an internal point of view, providing suggestions on what could be done for short- and long-term mental health improvement.

    • Muhammad Mainuddin Patwary
    • Sarya Swed
    • Sheikh Shoib
    Comment
  • The mental health implications of the 2023 Turkey–Syria earthquake will probably be profound. Here we present research from prior disasters related to the potential negative mental health effects of the earthquake and its aftermath and provide suggestions for mitigating potential deleterious consequences.

    • Dana Rose Garfin
    • Roxane Cohen Silver
    Comment
  • Socioeconomic inequalities are antecedents for poor mental health outcomes. Mental illness is highly prevalent internationally — impacting 1 in 8 people, with incidence of anxiety and depression skyrocketing during the pandemic. In the USA, one of the world’s wealthiest nations, the economic outlook remains bleak.

    • Stacia West
    • Amy Castro
    • P. Murali Doraiswamy
    Comment
  • Moving the needle in mental health research requires doing justice to the social, psychological, biological and developmental complexities that affect people in their living environments. We developed a comprehensive national research program to achieve scale and depth through translational project bundles focused on early recognition and prevention, urban mental health, and enhanced psychotherapy, underpinned by a range of shared infrastructures. The program was consistently co-created with and will involve people with lived experience at all stages of research.

    • Andreas Meyer-Lindenberg
    • Peter Falkai
    • Andreas Heinz
    Comment
  • Adolescents differ in their beliefs, or mindsets, about the nature and workings of their personal qualities. Here we present theory and data that show why changing adolescents’ mindsets can lead to more productive coping with challenging situations and improved mental health.

    • David S. Yeager
    • Carol S. Dweck
    Comment
  • Neurotechnologies that measure and modulate brain activity have not yet reached widespread clinical relevance. To accelerate translation into patient care, we propose three strategic adjustments in neurotechnology research — to consider the scope, scalability and stakeholders.

    • Markus Ploner
    • Alena Buyx
    • Simon N. Jacob
    Comment