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As evidence emerges describing the accumulation of small plastic particles in various organs and tissues of the body, a much deeper understanding of the effects of these particles on human health is urgently needed.
To make health systems more sustainable in the long-term, incentivize artificial intelligence (AI) and digital technologies that are grounded on careful testing and real-world validation.
Effective and sustainable interventions to address the global burden of mental disorders in children and adolescents require evidence-based research that fully acknowledges the social, cultural and economic challenges.
We are launching a new Series as a starting point for discussions on how to improve the health of women and girls as part of a route to achieving global health equity.
Governments need to invest in making assisted reproductive technology more accessible and equitable to counter staggering birth rate declines globally.
A year ago, we adopted an ethics framework to help with the assessment of and to increase transparency and accountability for research practices in studies involving partnerships between researchers in high- and low-income settings. We now reflect on our progress, what we learned and the way forward to champion ethical, inclusive and equitable partnerships in the content we publish.
Incretin-based drugs have demonstrated unprecedented efficacy in weight-loss trials, but ensuring that healthy body weight can be maintained is fundamental to sustainable good health.
The approval of two vaccines and a monoclonal antibody that target respiratory syncytial virus could shift the tide on the prevention and treatment of infection with this virus.
Twenty years after completion of the Human Genome Project, genetics is rapidly being integrated into everyday clinical practice. But in this era of genomic revolution, genetically trained teams of healthcare workers are needed to optimize delivery of patient care.
In this issue, we ask what it takes to build a healthier future for populations — a necessary condition to deliver on the commitments of the United Nations Sustainable Development Goals.
Dietary interventions have the potential to treat a wide variety of chronic conditions and diseases, but generating strong evidence and a framework for their integration into health systems will be critical for their success.
ChatGPT and other large language models may be able to enhance healthcare delivery and patients’ quality of life. But they will need to be tailored to specific clinical needs first.
The international community needs to prioritize research on interventions and preventative measures for dementia that are likely to produce the greatest global impact.
We are launching a series on evidence in medicine, to discuss new approaches to assessing the safety and efficacy of cutting-edge health technologies and treatments.
Checkpoint-blockade immunotherapy has transformed cancer therapeutics but still benefits only a subset of patients. The development of more-robust biomarkers of response could change that.
New initiatives aimed at reducing the burden of diabetes are laudable, but they will have to account for the disease’s complexity and heterogeneity to be truly effective and equitable at a global scale.
In this issue, Nature Medicine presents the Burden of Proof studies led by the Institute for Health Metrics and Evaluation, which quantitatively evaluate the strength of evidence of risk–outcome relationships to better inform effective clinical and policy recommendations.