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    Viral hepatitis is a global public health problem, and the burden of disease is increasing. In 2016, spurred by development of effective new treatments for hepatitis C and expanding access to hepatitis B vaccination, the 194 Member States of the WHO committed to eliminating viral hepatitis as a public health threat by 2030. Here, Nature Reviews Gastroenterology & Hepatology explores areas vital to meeting this ambitious target, from basic viral research to public policy.

    Image: KATERYNA KON/SCIENCE PHOTO LIBRARY
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    In this article series by Nature Reviews Gastroenterology & Hepatology, basic, translational and clinical topics in neurogastroenterology are explored.

    Image: Laura Marshall
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    In this article series, Nature Reviews Gastroenterology & Hepatology examines the cutting-edge techniques and technologies currently applied in gastrointestinal and liver research and clinical practice, and the approaches that might be available to investigators, clinicians and surgeons in the future.

    Image: PhotoDisc/ Getty Images
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    Fuelled by increasing obesity rates, metabolic dysfunction associated steatotic liver disease (MASLD, formerly known as NAFLD) has emerged as a leading global cause of chronic liver disease in the past few decades. Despite growing prevalence, the factors influencing MASLD development and subsequent progression to metabolic dysfunction associated steatohepatitis (MASH), liver fibrosis, cirrhosis and hepatocellular carcinoma are poorly understood. In this article series, Nature Reviews Gastroenterology & Hepatology explores the epidemiology of MASLD, disease mechanisms and therapeutics, and clinical approaches to diagnosis and management.

    Image: Caio Bracey
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    The gastrointestinal system comprises a plethora of different cell types that develop, interact, specialize and function in a complex, tightly regulated process and, in many cases, show remarkable plasticity. In this article series, Nature Reviews Gastroenterology & Hepatology explores different cell biology and developmental pathways involved in gastrointestinal health and disease, the role of stem and progenitor cells in tissue development and regeneration and recent advances in bioengineering, which might shape clinical approaches in the near future.

    Image: PASIEKA