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  • Collection |

    Selected, recent articles from across the Nature Portfolio that document the recent progress in understanding the biology of EV-mediated cell–cell communication and advances in clinical translation of EVs.

    Image: Vicky Summersby

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    This Collection provides an overview of current progress in developing targeted genome editing technologies, including a selection of protocols for using and adapting these tools in your own lab.

    Image: LuckyStep48 / Alamy Stock Vector

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    One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated experimental approaches have rejuvenated the field. In addition, cell cycle regulators have emerged as cancer therapy targets. This collection showcases ground-breaking cell cycle papers and reviews, ranging from basic discoveries to clinical applications.

    Image: Nicolas Plachta, NCB (2022)

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    Research interest is growing in profiling noncoding RNAs and understanding their biological functions in health and disease contexts.

    Image: Jeren (France) / Getty Images

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    This Collection showcases recent articles from Nature Cell Biology, Nature Metabolism and Nature Reviews Molecular Cell Biology covering cellular to systemic metabolic regulation. This selection accompanies the Nature Conference “Metabolic Communication Across Biological Scales” and provides a resource about current trends and directions in this field.

    Image: V. Summersby

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    The 2021 Nobel Prize in Physiology or Medicine was awarded to David Julius and Ardem Patapoutian "for their discoveries of receptors for temperature and touch."

    Image: Springer Nature/The Nobel Foundation/Imagesource

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    This collection of primary research articles, reviews and protocols focuses on an emerging topic of mechanobiology, highlighting the broad involvement of mechanical forces in different biological contexts, their roles in development, physiology and disease, and how these forces are sensed and transduced to produce biologically-relevant responses. The collection also showcases new technical approaches to modulate mechanobiology, which in the future could be used to control cell fate and behaviour for therapeutic benefits.

    Image: Vicky Summersby

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    The 2020 Nobel Prize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer Doudna for their pioneering work in gene-editing.

    Image: Springer Nature/The Nobel Foundation/Imagesource

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    NRMCB is 20! To mark this anniversary, we selected Review articles in 10 core areas of the journal. The Reviews are presented in pairs, an older and a more recent one, alongside 10 commissioned Journal Clubs — together the articles showcase developments and key discoveries in each research field.

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    This collection includes recent articles from across the Nature group of journals and showcases both the latest advances in the methodologies used to study genome organization, and our recent understanding of how genome organization and nuclear architecture regulate gene expression, cell fate and cell function in physiology and disease.

    Image: V. Summersby