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Volume 23 Issue 5, May 2022

‘Tiled traces’, inspired by the Review on p275.

Cover design: Rachael Tremlett.

Research Highlights

  • Bright light exerts antinociceptive effects in mice by activating a visual circuit involving the periaqueductal grey.

    • Darran Yates
    Research Highlight

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  • Hyperexcitability of a population of arousal-promoting neurons in the hypothalamus drives sleep instability in aged mice.

    • Katherine Whalley
    Research Highlight
  • The rapid switch from movement planning to execution is mediated by midbrain neurons that transmit information to cortex via the thalamus.

    • Sian Lewis
    Research Highlight
  • Two studies identify a mechanism linking TDP-43 pathology with genetic variants associated with increased risk of neurodegenerative disorders.

    • Natasha Bray
    Research Highlight
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Reviews

  • People may respond to listening to music by physically moving or feeling emotions. In this Review, Peter Vuust and colleagues discuss how music perception and related actions, emotions and learning are associated with the predictive capabilities of the human brain, with a focus on their predictive coding of music model.

    • Peter Vuust
    • Ole A. Heggli
    • Morten L. Kringelbach
    Review Article
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Perspectives

  • The past two decades have witnessed considerable interest in linking interindividual differences in behaviour to differences in brain structure. In this Perspective, Genon et al. examine how the study of brain structure–behaviour associations in healthy populations has developed during this period and the current challenges for this field.

    • Sarah Genon
    • Simon B. Eickhoff
    • Shahrzad Kharabian
    Perspective
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