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The levels of neurotransmitters and neuromodulators have been difficult to track. In this Review, Wu et al. give an overview of conventional and modern tools and imaging methods for monitoring neurochemicals, with a focus on genetically encoded sensors.
Genetic mosaicism has provided a new conceptual framework for the study of the human brain. In this Review, Bizzotto and Walsh discuss mechanisms of brain somatic mutations, what they reveal about development and pathology, and the major associated technical challenges.
People may respond to listening to music by physically moving or feeling emotions. In this Review, Peter Vuust and colleagues discuss how music perception and related actions, emotions and learning are associated with the predictive capabilities of the human brain, with a focus on their predictive coding of music model.
The past two decades have witnessed considerable interest in linking interindividual differences in behaviour to differences in brain structure. In this Perspective, Genon et al. examine how the study of brain structure–behaviour associations in healthy populations has developed during this period and the current challenges for this field.