Gene duplication articles within Nature Communications

Featured

• Article
  13 July 2021 | Open Access

  DNA transposons mediate duplications via transposition-independent and -dependent mechanisms in metazoans

  Transposons are accepted as evolutionary catalysts but how they do so remains less clear. Analyzing 100 animal genomes finds that terminal inverted repeat-type transposable elements catalyze new gene structures and new genes in animals via both transposition-independent and -dependent mechanisms.

  • Shengjun Tan
  • , Huijing Ma
  •  & Yong E. Zhang

• Article
  07 October 2016 | Open Access

  Evolutionary interplay between sister cytochrome P450 genes shapes plasticity in plant metabolism

  Genes in the cytochrome P450 family have evolved a wide range of functions. Here, Liu et al. reconstruct the evolution of the P450 genes CYP98A8 and CYP98A9in the Brassicales, revealing a complex history of retrotransposition, tandem duplication and neofunctionalization, followed by subfunctionalization or gene loss in specific lineages.

  • Zhenhua Liu
  • , Raquel Tavares
  •  & Hugues Renault

• Article
  17 November 2015 | Open Access

  Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney

  The genetic basis of clear cell sarcomas of the kidney is not well understood. In this study, Roy et al. perform whole-exome and RNA sequencing of these tumours and identify recurrent internal tandem duplications in BCOR, a key constituent of a variant polycomb repressive complex.

  • Angshumoy Roy
  • , Vijetha Kumar
  •  & D. Williams Parsons

• Article | 05 March 2015

  Remodelling of a homeobox gene cluster by multiple independent gene reunions in Drosophila

  Gene clusters of paralogous genes are thought to result from tandem gene duplications. Here, the authors show two independent reunions of homeobox genes in Drosophila, which suggests that large-scale chromosomal rearrangements play a role in reshaping paralogous gene clustering.

  • Carolus Chan
  • , Suvini Jayasekera
  •  & José M. Ranz

• Article
  22 April 2014 | Open Access

  The rainbow trout genome provides novel insights into evolution after whole-genome duplication in vertebrates

  Although whole-genome duplications (WGDs) are rare events, they have an important role in shaping vertebrate evolution. Here, the authors sequence the rainbow trout genome and show that rediploidization after WGD occurs in a slow and stepwise manner.

  • Camille Berthelot
  • , Frédéric Brunet
  •  & Yann Guiguen

• Article
  30 August 2011 | Open Access

  A segmental genomic duplication generates a functional intron

  The appearance of a new intron that splits an exon without disrupting the corresponding peptide sequence is a rare event in vertebrate genomes. Hellstenet al.demonstrate that, under certain circumstances, a functional intron can be produced in a single step by segmental genomic duplication.

  • Uffe Hellsten
  • , Julie L. Aspden
  •  & Daniel S. Rokhsar