Organogenesis articles within Nature Communications

Featured

• Article
  27 March 2013 | Open Access

  Trunk exoskeleton in teleosts is mesodermal in origin

  Trunk exoskeleton elements of non-tetrapods such as scales and fin rays are believed to derive from the neural crest. Shimada and colleagues use long-term cell labelling methods to show that these elements are actually derived from the mesoderm.

  • Atsuko Shimada
  • , Toru Kawanishi
  •  & Hiroyuki Takeda

• Article | 29 January 2013

  The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth

  Kidney maintenance and function are essential for a healthy organism. Here Nishinakamura and colleagues show that the phosphatase Dullard suppresses BMP signalling and apoptosis in the mouse kidney and that Dullard is required for the maintenance of functional nephrons after birth.

  • Masaji Sakaguchi
  • , Sazia Sharmin
  •  & Ryuichi Nishinakamura

• Article | 18 December 2012

  The developmental basis of bat wing muscle

  Phylogenetic bat studies suggest that powered flight is evolutionarily conserved. Tokita et al.find that bat wing muscles are derived from multiple myogenic sources with different embryonic origins, and that spatiotemporal correlations exist between outgrowth of wing membranes and expansion of wing muscles.

  • Masayoshi Tokita
  • , Takaaki Abe
  •  & Kazuo Suzuki

• Article
  22 March 2011 | Open Access

  Comparative transcriptome analysis reveals vertebrate phylotypic period during organogenesis

  The conservation of embryonic development across species is of great interest in evolutionary biology. Here, using transcriptome analysis, the authors show that the pharyngula stage of development—in mid-embryogenesis—is conserved between mice, chickens, frogs and zebrafish.

  • Naoki Irie
  •  & Shigeru Kuratani

• Article
  27 July 2010 | Open Access

  Identification of Thymosin β4 as an effector of Hand1-mediated vascular development

  The Hand1 transcription factor plays a central role in cardiovascular development. Here the authors demonstrate that Hand1 regulates thymosin β4 and that the delivery of synthetic thymosin β4 can rescue some of the vascular defects in Hand1 null mouse embryos.

  • Nicola Smart
  • , Karina N. Dubé
  •  & Paul R. Riley

• Article
  27 July 2010 | Open Access

  Ouabain protects against adverse developmental programming of the kidney

  Poor maternal nutrition is known to affect fetal kidney development. This study shows that the sodium potassium ATPase ligand, ouabain, protects kidneys from cell death induced by serum starvationin vitro and from abnormal kidney development due to a low-protein diet in vivo.

  • Juan Li
  • , Georgiy R. Khodus
  •  & Anita Aperia

• Article
  12 April 2010 | Open Access

  Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

  During development Sox transcription factors play important roles in the determination of cell fate. In this study Bhattaram and colleagues show that Sox4, Sox11 and Sox12 act redundantly in mouse development and are important for the maintenance of neural and mesenchymal progenitor cells.

  • Pallavi Bhattaram
  • , Alfredo Penzo-Méndez
  •  & Véronique Lefebvre

• Article
  12 April 2010 | Open Access

  The molecular network governing nodule organogenesis and infection in the model legume Lotus japonicus

  Plant and bacteria symbiosis in some species results in the coordinate formation of nitrogen fixing nodules and infection of the plant host. Using mutantLotus japonicusplants, Madsen and colleagues have determined the role of 16 different genes in these two processes.

  • Lene H. Madsen
  • , Leïla Tirichine
  •  & Jens Stougaard