Nature Genetics - Current issue : December 2008 - Vol 40 No 12
- Alternative splicing
- PTEN redundant in intestinal epithelium
- PNPLA3 coding variants in fatty liver disease
Latest highlights
Advance online publication
Mutation in reticular dysgenesis
Letter by Ulrich PannickeTwo groups independently report that mutations in the gene encoding adenylate kinase 2 cause reticular dysgenesis, a rare human immunodeficiency syndrome. It is the first to be classified as a mitochondriopathy.
Current issue
Genomic disorder on 1q21.1
Letter by Nicola Brunetti-PierriAnkita Patel and colleagues report microdeletions and microduplications at chromosome 1q21.1 in a series of individuals with features of microcephaly and macrocephaly, as well as developmental delay and neuropsychiatric abnormalities.
Current issue
Clonal interference in a eukaryote
Letter by Katy Kao & Gavin SherlockKaty Kao and Gavin Sherlock report a detailed molecular characterization of experimental evolution in Saccharomyces cerevisiae, providing support for the clonal interference and multiple mutation models of adaptive evolution.
Current issue
From annual to perennial
Letter by Siegbert MelzerSiegbert Melzer and colleagues report that in Arabidopsis the absence of MADS box proteins SOC1 and FUL leads to phenotypes of perennial woody plants, with indeterminate meristems, secondary growth with wood formation, and recurrent growth cycles.
Poster and podcast
Next-generation sequencing technologies
Nature Genetics and Nature Reviews Genetics present a poster and podcast that explore the conceptual basis of next-generation sequencing technologies, their myriad applications and the challenges for the future. Access to both is free, thanks to support from Applied Biosystems.
Conference
Mitochondrial Dysfunction in Neurological Disease
ConferenceIn collaboration with Nature Neuroscience and the Fondation IPSEN, we are pleased to announce a one-day symposium on mitochondrial dysfunction in neurological disease, to be held in Durham, North Carolina on December 5. The meeting aims to bring together geneticists, neuroscientists and cell biologists to highlight recent advances in this field.
